INTRODUCTION Fungi are free-living microorganisms that exist as yeasts (single-cell, round fungi), molds (multicellular filamentous fungi), or a combination of the two (so-called dimorphic fungi). All fungi are eukaryotic organisms….
Pharmacology of Hematopoiesis and Immunomodulation Andrew J. Wagner, Ramy A. Arnaout, and George D. Demetri INTRODUCTION & CASE PHYSIOLOGY OF HEMATOPOIESIS Central Role of Hematopoietic Growth Factors Multilineage Growth Factors…
INTRODUCTION Drugs are typically administered in either pill or injection form, with limited control over release rate and localization. More advanced drug delivery systems have recently been developed, however. The…
Principles of Nervous System Physiology and Pharmacology Joshua M. Galanter, Susannah B. Cornes, and Daniel H. Lowenstein INTRODUCTION & CASE NEUROANATOMY Anatomy of the Peripheral Nervous System Autonomic Nervous System…
INTRODUCTION Environmental toxicology is the study of deleterious effects of physical, chemical, or microbiological agents present in air, water, food, or other media. In this context, airborne exposures include those…
Systematic Detection of Adverse Drug Events Jerry Avorn INTRODUCTION & CASE CHALLENGES IN THE ASCERTAINMENT OF DRUG SAFETY Study Size and Generalizability Surrogate Outcomes and Comparators Duration and Postapproval Studies…
Pharmacology of the Thyroid Gland Anthony Hollenberg and William W. Chin INTRODUCTION & CASE THYROID GLAND PHYSIOLOGY Synthesis and Secretion of Thyroid Hormones Metabolism of Thyroid Hormones Effects of Thyroid…
Adrenergic Pharmacology Nidhi Gera, Ehrin J. Armstrong, and David E. Golan INTRODUCTION & CASE BIOCHEMISTRY AND PHYSIOLOGY OF ADRENERGIC FUNCTION Catecholamine Synthesis, Storage, and Release Reuptake and Metabolism of Catecholamines…
INTRODUCTION Our tissues are exposed on a daily basis to xenobiotics—foreign substances that are not naturally found in the body. Most drugs are xenobiotics that are used to modulate bodily…
Drug Transporters Baran A. Ersoy and Keith A. Hoffmaster INTRODUCTION & CASE UPTAKE AND EFFLUX TRANSPORTERS Uptake Transporters Organic Anion-Transporting Polypeptide (OATP) Family Organic Anion Transporter (OAT) Family Organic Cation…
