Infectious Mononucleosis Bruce M. Wenig, MD Key Facts Terminology Systemic, benign, self-limiting infectious lymphoproliferative disease primarily caused by, but not limited to, Epstein-Barr virus (EBV) infection Etiology/Pathogenesis EBV estimated to…
Dermoid Cyst Bruce M. Wenig, MD Key Facts Terminology Benign, developmental cystic anomaly originating from ectoderm and mesoderm, but not endoderm Clinical Issues May occur over wide age range but…
Protocol for the Examination of Nasal Cavity and Paranasal Sinus Specimens Lester D. R. Thompson, MD Nasal Cavity and Paranasal Sinuses Incisional Biopsy, Excisional Biopsy, Resection Specimen (select all that…
Malignant Fibrous Histiocytoma/Undifferentiated Pleomorphic Sarcoma Bruce M. Wenig, MD Key Facts Terminology High grade, pleomorphic, malignant, mesenchymal Diagnosis is one of excluding another more specific sarcoma or nonsarcomatous neoplasm Etiology/Pathogenesis…
Malignant Peripheral Nerve Sheath Tumor Bruce M. Wenig, MD Key Facts Terminology Malignant tumor of peripheral nerves or having differentiation along the lines of various elements of nerve sheath Occurs…
Leiomyosarcoma Bruce M. Wenig, MD Key Facts Terminology LMS: Malignant tumor of smooth muscle Etiology/Pathogenesis May develop following irradiation or cyclophosphamide exposure Appears to arise from vascular structures Link between…
Malignant Mucosal Melanoma Lester D. R. Thompson, MD Key Facts Terminology Neural crest-derived neoplasms originating from melanocytes and demonstrating melanocytic differentiation Clinical Issues Anterior nasal septum > maxillary sinus Overall…
Squamous Cell Carcinoma Bruce M. Wenig, MD Key Facts Terminology Malignant epithelial neoplasm arising from surface epithelium with squamous cell differentiation Etiology/Pathogenesis Associated risk factors include Nickel exposure, exposure to…
Ectopic Pituitary Adenoma Lester D. R. Thompson, MD Key Facts Terminology Benign pituitary gland neoplasm occurring separately from and without involvement of sella turcica (a normal anterior pituitary gland) Clinical…
Glomangiopericytoma (Sinonasal-type Hemangiopericytoma) Lester D. R. Thompson, MD Key Facts Terminology Soft tissue tumor showing perivascular myoid differentiation Clinical Issues Nasal cavity is usually affected in isolation Present with nasal…
