Cutaneous and Systemic Mastocytosis Jeremy C. Wallentine, MD Key Facts Terminology Heterogeneous group of clonal neoplastic proliferations of mast cells in ≥ 1 organ system Cutaneous mastocytosis: Confined to skin…
Cutaneous Gamma-Delta T-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology T-cell lymphoma of mature γδ cells Separately classified from SPTCL in WHO (2008) Clinical Issues Hemophagocytic syndrome in 45%…
Subcutaneous Panniculitis-like T-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology T-cell lymphoma of αβ cells usually involving subcutaneous tissue with prominent karyorrhexis and cytotoxic phenotype Cases composed of γδ…
Systemic T-cell and NK-cell Lymphomas Involving the Skin Aaron Auerbach, MD, PhD Key Facts Terminology Systemic T-cell or NK-cell lymphoma that has spread to the skin Morphology of primary and…
Common Acquired Melanocytic Nevi Christine J. Ko, MD Key Facts Clinical Issues Majority develop in adolescence Microscopic Pathology Flat surface to slightly raised to polypoid Epidermis varies (e.g., thin or…
Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology T-cell lymphoma of skin with small to medium-sized CD4(+) T cells and usually indolent clinical course…
Mycosis Fungoides (and Subtypes) Sa A. Wang, MD Key Facts Terminology Primary cutaneous T-cell lymphoma characterized by Epidermotropism Clinical course showing stepwise evolution of patches, plaques, and tumors Clinical Issues…
Congenital Melanocytic Nevi Christine J. Ko, MD Key Facts Clinical Issues Present at birth, by definition However, some congenital melanocytic nevi may be “tardive” and not readily noticeable at birth…
Extranodal NK/T-cell Lymphoma, Nasal Type Aaron Auerbach, MD, PhD Key Facts Terminology Tumor of NK cells or T cells, with necrosis, Epstein-Barr virus infection, and angioinvasion Etiology/Pathogenesis Epstein-Barr virus Clinical…
Primary Cutaneous Anaplastic Large Cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology One of the primary cutaneous CD30(+) T-cell lymphoproliferative disorders T-cell lymphoma of atypical, usually large CD30(+) cells,…
