Basicmedical Key

Congenital Surfactant Deficiency Billie Fyfe, MD Eileen McKay, MD Key Facts Terminology Variable patterns of acute and chronic diffuse lung disease in neonates, children, and rarely adults due to genetic…

Dyshormonogenetic Goiter Vania Nosé, MD, PhD Key Facts Terminology Familial goiter that develops from defect in the metabolism of thyroid hormone secondary to an inherited disorder Etiology/Pathogenesis Multiple inherited biochemical…

Cavernous Hemangioma Brock Kaya, MD Key Facts Terminology Angiographically occult vascular malformation composed of uniform blood vessels with fibrous walls Clinical Issues Account for 10-15% of all vascular malformations Majority…

Cat Scratch Disease Irina Margaritescu, MD, DipRCPath Bruce R. Smoller, MD Key Facts Etiology/Pathogenesis Domestic cats represent natural reservoir and vectors Cat scratch disease (CSD) is caused by Bartonella henselae…

Molluscum Contagiosum Talley Whang, MD Key Facts Etiology/Pathogenesis Caused by molluscum contagiosum viruses (poxvirus), transmitted by skin-to-skin contact Clinical Issues Primarily affects young children; also affects immunosuppressed individuals Dome-shaped papules…

Impetigo Irina Margaritescu, MD, DipRCPath Bruce R. Smoller, MD Key Facts Terminology Definition Acute, contagious superficial pyogenic infection of skin caused by staphylococci, streptococci, or both Clinical Issues Epidemiology Peak…

Darier Disease Irina Margaritescu, MD, DipRCPath Key Facts Etiology/Pathogenesis Autosomal dominant genodermatosis Mutations in gene ATP2A2 New mutations in ˜ 25% of cases Clinical Issues Age Typical onset in late…

Chalazion Larissa V. Furtado, MD Key Facts Etiology/Pathogenesis Chronic obstruction of meibomian or Zeis glands → retained meibomian secretions → chronic granulomatous inflammation Clinical Issues Occurs more frequently on the…

Epidermolysis Bullosa, Inherited Jessica M. Comstock, MD Key Facts Terminology Heterogeneous group of noninflammatory inherited disorders characterized by development of blisters or erosions after minor trauma Etiology/Pathogenesis Autosomal dominant or…

Acropustulosis of Infancy Larissa V. Furtado, MD Key Facts Terminology Infantile acropustulosis Clinical Issues Predominantly occurs during first 3 years of life Not limited to young children Involves primarily acral…