Trichofolliculoma

 May also represent later stage/regressing variant of trichofolliculoma, but is typically dermal-based tumor with prominent sebaceous glands



• Dilated pore of Winer
image Cystically dilated follicle that communicates with overlying epidermis

• Trichoepithelioma
image Lobules and nests of basaloid epithelium with peripheral palisading

image Lacks central folliculocystic structure

• Dermoid cyst
image Cystic lesion lined by bland squamous epithelium with follicular structures and sebaceous glands



image
Trichofolliculoma
Trichofolliculoma is an invaginated cystic tumor lined by keratinizing squamous epithelium that communicates with the overlying epidermis. The central cystic space is usually filled with keratinous debris.


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Trichofolliculoma
Trichofolliculoma is characterized by an invaginated cystic lesion lined by mature, keratinizing squamous epithelium that communicates with the overlying epidermis.

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Trichofolliculoma With Radiating Follicular Structures
Small, branching follicular structures image radiate out from, and communicate with, the central cystic space.

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Trichofolliculoma With Primitive Radiating Follicular Structures
Radiating around the central cystic space are numerous primitive follicles that connect with the central cystic space. The follicles often show secondary branching image.


TERMINOLOGY


Definitions




• Hamartoma with prominent follicular differentiation


ETIOLOGY/PATHOGENESIS


Unknown




• Majority of cases are sporadic


CLINICAL ISSUES


Epidemiology




• Incidence
image Rare

• Age
image Usually presents in adults

• Sex
image Males and females equally affected


Presentation




• Dome-shaped papule with central dilated pore
image Tuft of white hairs often emerges from opening

• Face is most common location, especially around nose

• Occasionally on scalp, neck, or other locations

Apr 24, 2017 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Trichofolliculoma
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