May also represent later stage/regressing variant of trichofolliculoma, but is typically dermal-based tumor with prominent sebaceous glands
• Dilated pore of Winer
Cystically dilated follicle that communicates with overlying epidermis
• Trichoepithelioma
Lobules and nests of basaloid epithelium with peripheral palisading
Lacks central folliculocystic structure
• Dermoid cyst
Cystic lesion lined by bland squamous epithelium with follicular structures and sebaceous glands
Trichofolliculoma Trichofolliculoma is an invaginated cystic tumor lined by keratinizing squamous epithelium that communicates with the overlying epidermis. The central cystic space is usually filled with keratinous debris.
Trichofolliculoma Trichofolliculoma is characterized by an invaginated cystic lesion lined by mature, keratinizing squamous epithelium that communicates with the overlying epidermis.
Trichofolliculoma With Radiating Follicular Structures Small, branching follicular structures radiate out from, and communicate with, the central cystic space.
Trichofolliculoma With Primitive Radiating Follicular Structures Radiating around the central cystic space are numerous primitive follicles that connect with the central cystic space. The follicles often show secondary branching .
TERMINOLOGY
Definitions
• Hamartoma with prominent follicular differentiation
ETIOLOGY/PATHOGENESIS
Unknown
• Majority of cases are sporadic
CLINICAL ISSUES
Epidemiology
• Incidence
Rare
• Age
Usually presents in adults
• Sex
Males and females equally affected
Presentation
• Dome-shaped papule with central dilated pore
Tuft of white hairs often emerges from opening
• Face is most common location, especially around nose
• Occasionally on scalp, neck, or other locations
Treatment
• Surgical approaches
Simple excision is curative
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radiate out from, and communicate with, the central cystic space.
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