2 Thyroid Diseases
Thyroid and Parathyroid Anatomy
Thyroid
• Thyroid typically consists of right and left lobes, connected by a midline isthmus, with an ascending pyramidal lobe in about 50% of cases.
• Location
Immediately anterior and lateral to trachea, from about 5th cervical vertebra to 1st thoracic vertebra
• Surgical (false) capsule lies external to the true capsule and is derived from the pretracheal fascia.
• Of the overlying strap muscles, the sternohyoid is most superficial, overlying the sternothyroid and thyrohyoid.
• Thyroid follicular (epithelial/principal) cells secrete thyroxine (T4) and triiodothyronine (T3), regulated by TSH receptors.
• Thyrotropin-releasing factor or hormone (TRF or TRH) from hypothalamus controls TSH release from pituitary.