2 Thyroid Diseases
Thyroid and Parathyroid Anatomy
Thyroid
• Thyroid typically consists of right and left lobes, connected by a midline isthmus, with an ascending pyramidal lobe in about 50% of cases.
• Location
Immediately anterior and lateral to trachea, from about 5th cervical vertebra to 1st thoracic vertebra
Immediately anterior and lateral to trachea, from about 5th cervical vertebra to 1st thoracic vertebra• Surgical (false) capsule lies external to the true capsule and is derived from the pretracheal fascia.
• Of the overlying strap muscles, the sternohyoid is most superficial, overlying the sternothyroid and thyrohyoid.
• Thyroid follicular (epithelial/principal) cells secrete thyroxine (T4) and triiodothyronine (T3), regulated by TSH receptors.
• Thyrotropin-releasing factor or hormone (TRF or TRH) from hypothalamus controls TSH release from pituitary.

