Testicular Regression Syndrome

Testicular Regression Syndrome

Larissa V. Furtado, MD

Characteristic pathologic features of testicular regression syndrome include vascularized fibroconnective tissue with hemosiderin-laden macrophages image. Seminiferous tubules are rarely identified.

Testicular regression syndrome shows a fibrovascular nodule with foci of dystrophic calcification image. These findings suggest the role of remote vascular compromise in the etiology of this entity.



  • Embryonic testicular regression syndrome

  • Vanishing testes syndrome



  • Unknown

    • Result from atrophy and disappearance in fetal life of an initially normal testis

    • Thought to be the result of intrauterine or perinatal vascular compromise


Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Testicular Regression Syndrome
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