Compatibility of drugs in a syringe driver for subcutaneous use
Notes 1 Cyclizine is likely to precipitate in the presence of sodium chloride 0.9%. In addition, the solubility of cyclizine is reduced by the presence of other medicines in solution….
Factors influencing medicine stability and compatibility of injectable medicines
13.1 Degradation 13.1.1 In aqueous solution On reconstitution, dry powder medicines are relatively unstable in aqueous vehicles and normally degrade by hydrolysis (decomposition of a substance by a chemical reaction…