Chapter 11 Physiology and Pharmacology of Opioid Analgesics Chapter outline Groups of Opioids Underlying Mechanisms of Opioid Analgesia and Adverse Effects Endogenous Opioid System Opioid Receptors Pharmacologic Concepts Pharmacokinetics Pharmacodynamics…
Chapter 17 Intravenous Patient-Controlled Analgesia Chapter outline Initial Intravenous Patient-Controlled Analgesia (PCA) Prescription Bolus Dose and Lockout Interval Hour Limit Continuous Infusion (Basal Rate) PCA in Opioid-Tolerant Patients Loading Dose…
Chapter 13 Guidelines for Opioid Drug Selection Chapter outline Characteristics of Selected Mu Agonist Opioids Morphine Codeine Fentanyl Hydrocodone Hydromorphone Levorphanol Meperidine Methadone Oxycodone Oxymorphone Propoxyphene Other Mu Opioid Analgesics…
Chapter 7 Individualizing the Selection of Nonopioid Analgesics Chapter outline General Considerations Acute versus Persistent (Chronic) Pain Analgesic History Pain Intensity Current Analgesic Response Frequency of Dosing Routes of Administration…
Chapter 6 Adverse Effects of Acetaminophen and NSAIDs Chapter outline Adverse Effects of Acetaminophen Hepatic Effects Renal Effects Cardiovascular (CV) Effects Hematologic Effects and Anticoagulant Therapy Gastrointestinal (GI) Effects Adverse…
Chapter 26 Adjuvant Analgesics for Postoperative and Other Acute Pain Chapter outline Continuous Peripheral Nerve Block Catheter Placement Research on the Use of Continuous Peripheral Nerve Block Efficacy Compared with…
Chapter 12 Key Concepts in Analgesic Therapy Chapter outline Multimodal Analgesia WHO Analgesic Ladder for Cancer Pain Relief Steps 1, 2, and 3 Effectiveness of the WHO Analgesic Ladder Preemptive…
Chapter 23 Adjuvant Analgesics for Persistent (Chronic) Neuropathic Pain Chapter outline Anticonvulsant Drugs “Newer” Second-Generation Anticonvulsants First-Generation Anticonvulsants Summary Mechanism of Action Adverse Effects Other Second-Generation Anticonvulsants Indications Drug Selection…
Chapter 30 Adjuvant Analgesics for Malignant Bowel Obstruction Chapter outline Anticholinergic Drugs Octreotide Corticosteroids Conclusion BOWEL obstruction can occur in any patient with cancer but is most common in those…
Chapter 22 Multipurpose Adjuvant Analgesics Chapter outline Antidepressant Drugs Tricyclic Antidepressants (TCAs) “Newer” Antidepressants Selective Serotonin Reuptake Inhibitors (SSRIs) Summary Mechanism of Action Adverse Effects Indications Drug Selection Dose Selection…
