Molecular Biology of T-Cell Lymphoma Anjali Mishra Pierluigi Porcu INTRODUCTION T-cell lymphomas represent a group of lymphoproliferative disorders of T-cell origin. T-cell lymphomas tend to be rare, heterogeneous, and more…
Mononuclear Phagocytes of the Skin Sena J. Lee András Schaffer INTRODUCTION The mononuclear phagocyte system (MPS) is composed of at least three subsets of tissue histiocytes including monocytes, macrophages, and…
NK Cell Immunobiology Aharon G. Freud INTRODUCTION Natural killer (NK) cells are innate lymphoid cells (ILCs) that have a characteristic large granular lymphocyte morphology and that are able to recognize…
Cutaneous B-Cell Immunobiology Alejandro A. Gru INTRODUCTION Originally termed skin-associated lymphoid tissue (SALT), the “skin immune system” (SIS) comprises specialized skin-resident immune cells, as well as immunocompetent skin-trophic lymphocytes constantly…
Cutaneous T-Cell Immunobiology Andy C. Hsi András Schaffer INTRODUCTION The skin is the largest organ of the human body and functions as a physical and immunologic barrier against external pathogens…
