Rheumatoid Arthritis

Nov 30, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on Rheumatoid Arthritis

380   Rheumatoid Arthritis Ankoor Shah, E. William St. Clair INTRODUCTION Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology marked by a symmetric, peripheral polyarthritis. It is the…

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Lower Gastrointestinal Cancers

Nov 30, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on Lower Gastrointestinal Cancers

FIGURE 105-4   Influence of vismodegib on the hedgehog (Hh) pathway. Normally, one of three Hh ligands (sonic [SHh], Indian, or desert) binds to patched homolog 1 (PTCH1), causing its degradation and…

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Diseases of the Spinal Cord

Nov 30, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on Diseases of the Spinal Cord

456 Diseases of the Spinal Cord Stephen L. Hauser, Allan H. Ropper   Diseases of the spinal cord are frequently devastating. They produce quadriplegia, paraplegia, and sensory deficits far beyond…

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Biology of Obesity

Nov 30, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on Biology of Obesity

FIGURE 411-1   Pubertal events in males. Sexual maturity ratings for genitalia and pubic hair and divided into five stages. (From WA Marshall, JM Tanner: Variations in the pattern of pubertal changes…

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Infectious Arthritis

Nov 30, 2016 by in GENERAL & FAMILY MEDICINE Comments Off on Infectious Arthritis

In patients with subacute presentations, fever is typically low-grade and rarely exceeds 39.4°C (103°F); in contrast, temperatures of 39.4°–40°C (103°–104°F) are often noted in acute endocarditis. Fever may be blunted…

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