Feasibility of Multinational Trials
Feasibility of Multinational Trials Put an idea into your intelligence, and leave it there an hour, a day, a year without ever having occasion to refer to it. When at…
Quality of Life and Pharmacoeconomics in Clinical Trials
Quality of Life and Pharmacoeconomics in Clinical Trials I am among those who think that science has great beauty. A scientist in his laboratory is not only a technician: he…
Dose-response Relationships in Clinical Trials
Dose-response Relationships in Clinical Trials There is no more difficult art to acquire than the art of observation, and for some men it is quite as difficult to record an…
Electronic Data Collection and E-clinical Trials
Electronic Data Collection and E-clinical Trials I still struggle with the same problems as ten years ago. I succeed in small matters but the real goal remains unattainable, even though…
Principles of Patient Recruitment and Retention
Principles of Patient Recruitment and Retention I will not let him stir Till I have used the approved means I have, With wholesome syrups, drugs, and holy prayers, To make…
Monitoring and Auditing a Clinical Trial
Monitoring and Auditing a Clinical Trial Neurotic means he is not as sensible as I am, and psychotic means he’s even worse than my brother-in-law. –Karl Menninger The grand aim…
Phase 4 Trials and Postapproval Pharmacovigilance Methodologies
Phase 4 Trials and Postapproval Pharmacovigilance Methodologies In science, ‘fact’ can only mean ‘confirmed to such a degree that it would be perverse to withhold provisional assent.’ I suppose that…
Groups that Influence Protocol Design
Groups that Influence Protocol Design The practice of medicine will be very much as you make it—to one a worry, a care, a perpetual annoyance; to another, a daily job…
Overview of Phase 4 and Postapproval Clinical Activities
Overview of Phase 4 and Postapproval Clinical Activities A theory is the more impressive the greater the simplicity of its premises, the more different kinds of things it relates, and…
Introduction to Clinical Trials
Introduction to Clinical Trials The history of drugs has never been a particularly attractive subject in medical education, and one reason for this is that it is so unbelievably deplorable…
