Basicmedical Key

Sarcoidosis Key Facts Etiology/Pathogenesis Etiology unknown, but evidence suggests it may represent exaggerated cellular immune response to an unidentified antigen Clinical Issues Most commonly affected sites include lungs (95% of…

Blastomycosis Key Facts Terminology Pulmonary infection caused by inhalation of the fungus Blastomyces dermatidis Clinical Issues Geographic distribution in the USA: Mississippi, Missouri, and Ohio River valleys Acute infection is…

Respiratory Bronchiolitis Key Facts Terminology Respiratory bronchiolitis-interstitial lung disease (RB-ILD) Synonym: Smoker’s bronchiolitis Mild form of interstitial lung disease Etiology/Pathogenesis Closely associated with smoking history Occupational exposure to fumes Clinical…

Bronchiolitis Obliterans with Organizing Pneumonia Key Facts Terminology Synonyms: Cryptogenic organizing pneumonia (COP), bronchiolitis obliterans Definition Idiopathic interstitial and airway disease process with features of pneumonia Etiology/Pathogenesis No definitive etiology…

Bronchocentric Granulomatosis Key Facts Terminology Reaction pattern of lung parenchyma characterized by broncho- and bronchiolocentric necrotizing granulomatous inflammation Clinical Issues Most cases of BCG are allergic and associated with allergic…

Protocol for Lung Cancer Specimen Examination Lung: Resection Surgical Pathology Cancer Case Summary (Checklist) Specimen ____ Lung ____ Lobe(s) of lung (specify): ______________________________ ____ Bronchus (specify): ______________________________ ____ Other (specify):…

Desquamative Interstitial Pneumonia Key Facts Terminology A distinctive histologic reaction pattern to lung injury related to cigarette smoking Clinical Issues Dyspnea Cough Cessation of smoking generally leads to regression of…

Lymphangioleiomyomatosis Key Facts Terminology Lymphangioleiomyomatosis (LAM) Etiology/Pathogenesis Unknown etiology May share similar genetic relationship with tuberous sclerosis complex Clinical Issues Incidence More common in premenopausal women Rarely described in children…

Idiopathic Pulmonary Hemosiderosis Key Facts Terminology Intrapulmonary hemorrhage of unknown etiology that is unassociated with other systemic manifestations Clinical Issues Affects children more commonly than adults About 20% of patients…

Paraffinoma (Lipoid Pneumonia) Key Facts Terminology Synonyms Cholesterol pneumonia, lipoid pneumonia, golden pneumonia Definition: Type of pneumonia that could be secondary to aspiration; can be classified as Endogenous Exogenous Etiology/Pathogenesis…