Capillary Hemangioma
Capillary Hemangioma Peter C. Burger, MD Key Facts Terminology Benign vascular tumor formed of multiple capillary-sized vessels with large feeding vessel Clinical Issues Intraspinal in most cases Nerve root (common)…
Capillary Hemangioma Peter C. Burger, MD Key Facts Terminology Benign vascular tumor formed of multiple capillary-sized vessels with large feeding vessel Clinical Issues Intraspinal in most cases Nerve root (common)…
Molecular Factors Index Molecular Factors Discussed Molecular Factor Chromosomal Location Definition/Alternative Names Chapters β-catenin (see CTNNB1) 1, loss of Prolactinoma 10, loss of Ganglion Cell Tumors; Glioblastoma; Meningioma; Papillary Tumor…
Antibody Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names Chapters α-fetoprotein alpha 1 fetoprotein AFP, Z5A06, clone C3 Atypical Teratoid/Rhabdoid Tumor; Germinoma; Metastatic Neoplasms, Intracranial and Intraspinal Meninges; Metastatic…
Melanotic Schwannoma Ayca Ersen, MD Bernd W. Scheithauer, MD Key Facts Clinical Issues Sporadic or syndromic (Carney complex) Macroscopic Features No encapsulation; occasionally interrupted, thin collagen layer with soft tissue…
Primary Melanocytic Neoplasms Elisabeth J. Rushing, MD Key Facts Terminology Spectrum from low-grade melanocytoma to malignant melanoma No consensus grading system Clinical Issues Sites Posterior fossa, spinal cord, supratentorial Prognosis…
Solitary Fibrous Tumor, Hemangiopericytoma Type Elisabeth J. Rushing, MD Key Facts Terminology Now considered part of solitary fibrous tumor (SFT) spectrum (“cellular” or “malignant” SFT), especially at systemic sites Clinical…
CNS Primitive Neuroectodermal Tumors Fausto J. Rodriguez, MD Key Facts Terminology Heterogeneous group of embryonal neoplasms composed of poorly differentiated cells that may express neuronal and glial markers Clinical Issues…
Embryonal Tumor with Abundant Neuropil and True Rosettes Peter C. Burger, MD Key Facts Terminology Relationship to ependymoblastoma debated Clinical Issues Usually < 3 years Intracranial, both supra- and infratentorial…
Peripheral Primitive Neuroectodermal Tumor (Ewing Sarcoma) Fausto J. Rodriguez, MD Key Facts Terminology Unrelated to intraparenchymal CNS PNETs Etiology/Pathogenesis Somatic rearrangements in EWS gene result in fusion transcripts with aberrant…
Gliomatosis Cerebri Peter C. Burger, MD Key Facts Terminology Defined largely by radiologic criteria Infiltrating glioma involving 3 or more lobes or compartments, often bilaterally Astrocytic, most cases; oligodendroglial, occasional…