Lecithin-Cholesterol Acyl Transferase Deficiency Ami Bhalodia, MD Key Facts Terminology Complete or partial LCAT deficiency Familial LCAT deficiency Fish eye disease Etiology/Pathogenesis Defect in LCAT-mediated cholesterol ester-formation Mutation of LCAT…
Rheumatoid Arthritis Neeraja Kambham, MD Key Facts Etiology/Pathogenesis Predominantly therapy related Tubulointerstitial nephritis and acute renal failure caused by NSAIDs MGN caused by gold salts, penicillamine, and TNF-α antagonists ANCA-related…
Immunotactoid Glomerulopathy Anthony Chang, MD Key Facts Terminology Congo red negative organized glomerular immunoglobulin deposits Clinical Issues Caucasian predilection Nephrotic syndrome, hematuria, and hypocomplementemia Often associated with monoclonal gammopathy or…
Classification of Cystic Diseases Helen Liapis, MD Joseph Gaut, MD, PhD Adult ADPKD kidneys are massively enlarged and contain numerous oval/spherical cysts dispersed throughout the cortex and medulla. Cysts are…
Blastomycosis Anthony Chang, MD Key Facts Etiology/Pathogenesis Blastomyces dermatitidis Endemic to central/southern United States, Canada Reported in Central/South America, Europe, and Africa Ubiquitous dimorphic fungus acquired by inhalation Macroscopic Features…
Lead and Other Heavy Metal Toxins Shane M. Meehan, MBBCh Key Facts Terminology Renal disease due to toxic effects of lead and other metals Etiology/Pathogenesis Principal toxic metals encountered include…
Tubulointerstitial Nephritis with Uveitis A. Brad Farris, III, MD Key Facts Terminology Tubulointerstitial nephritis with uveitis (TINU) Etiology/Pathogenesis Autoimmune, infectious, environmental, and genetic Most likely cause in most cases is…
Renal Lymphangiectasis Aleksandr Vasilyev, MD, PhD Key Facts Terminology Hamartomatous or acquired obstructive lesion resulting in cystic dilatation of kidney lymphatics Clinical Issues No age or gender predilection; may be…
Uric Acid Nephropathy/Gout Shane M. Meehan, MBBCh Key Facts Terminology Intrarenal precipitation of uric acid associated with hyperuricemia Etiology/Pathogenesis Decreased uric acid excretion (75-90%) Overproduction of uric acid (10-25%) Clinical…
Ethylene Glycol Shane M. Meehan, MBBCh Key Facts Terminology Oxalosis due to ethylene glycol ingestion Etiology/Pathogenesis Renal injury due to calcium oxalate deposition and other toxins like glycolic acid Clinical…
