Gastric Antral Vascular Ectasia Amitabh Srivastava, MD Key Facts Terminology GAVE, “watermelon stomach” Etiology/Pathogenesis Elderly patients, often with associated connective tissue disease Clinical Issues Upper GI bleeding or chronic occult…
Dysplasia in Barrett Esophagus Elizabeth A. Montgomery, MD Key Facts Clinical Issues No metastatic potential by itself High-grade dysplasia (HGD) In pooled data about 30% of patients with HGD progress…
Squamous Dysplasia Elizabeth A. Montgomery, MD Key Facts Terminology Precancerous squamous lesion that contains both architectural and cytologic abnormalities Confined to basement membrane Etiology/Pathogenesis More common in African-Americans than Caucasians…
Squamous Papilloma Elizabeth A. Montgomery, MD Key Facts Terminology Benign tumor composed of hyperplastic squamous epithelium, overlying finger-like cores of lamina propria Clinical Issues Recurrences rare Synchronous or metachronous carcinomas…
Barrett Esophagus Elizabeth A. Montgomery, MD Key Facts Terminology Columnar-lined esophagus Change of esophageal mucosa Any length Visibility at endoscopy Contains intestinal metaplasia on biopsy Outside USA: “Barrett esophagus” is…
HIV-associated Ulcers Laura W. Lamps, MD Key Facts Terminology Reportedly causes 40-50% of ulcers in HIV patients Clinical Issues Odynophagia, independent of food intake Chest pain Weight loss Macroscopic Features…
Corrosive Damage (Lye) Elizabeth A. Montgomery, MD Key Facts Terminology Lye injury, caustic injury Damage to esophagus caused by accidental or purposeful ingestion of caustic substances Clinical Issues Common in…
Gastroesophageal Reflux Disease Alexandros D. Polydorides, MD, PhD Key Facts Terminology Symptoms, lesions, or complications due to reflux Etiology/Pathogenesis LES defects, hiatal hernia, ↑ fluid volume, inefficient gastroesophageal clearance, lifestyle…
Esophageal Tears and Perforations Alexandros D. Polydorides, MD, PhD Key Facts Terminology MWT: Spontaneous mucosal gastroesophageal tear BS: Spontaneous transmural esophageal perforation Etiology/Pathogenesis Alcohol or salicylate use/abuse, hiatal hernia, portal…
Tracheoesophageal Fistula Alexandros D. Polydorides, MD, PhD Key Facts Terminology TEF: Congenital fistulous communication between trachea and proximal &/or distal esophagus EA: Complete interruption of lumen continuity Clinical Issues 0.02-0.04%,…
