Smooth Muscle Tumors

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Smooth Muscle Tumors

Smooth Muscle Tumors Gene Landon, MD Key Facts Clinical Issues Mostly in pelvis and retroperitoneum of middle-aged/elderly individuals Cytopathology Low-grade leiomyosarcoma (LMS): Plump spindle cells with cigar-shaped nuclei and fibrillar/finely…

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Metastatic Tumors

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Metastatic Tumors

Metastatic Tumors Dina R. Mody, MD Key Facts Clinical Issues Most common primary sites are lung, breast, prostate, kidney, and thyroid Predilection for regions containing red marrow Commonly involved bones…

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Giant Cell Tumor

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Giant Cell Tumor

Giant Cell Tumor Dina R. Mody, MD Key Facts Cytopathology Cellular aspirates that may be bloody Dispersed or checkerboard pattern of giant cells and uninucleate stromal cells, which may be…

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Solid Pseudopapillary Neoplasm

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Solid Pseudopapillary Neoplasm

Solid Pseudopapillary Neoplasm Gene Landon, MD Key Facts Clinical Issues Typically in young females, in body/tail of pancreas Cytopathology Pseudopapillae with tumor cell layer(s) arranged around capillaries ± metachromatic myxoid…

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Urothelial Carcinoma

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Urothelial Carcinoma

Urothelial Carcinoma Yimin Ge, MD Key Facts Clinical Issues 5-10% of renal tumors, 90% of pelvicalyceal tumors Mean age: 67-70 years, M:F = 1.7-2:1 Cytopathology Hypercellular aspirate Multilayered sheets, papillae,…

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Renal Medullary Carcinoma

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Renal Medullary Carcinoma

Renal Medullary Carcinoma Yimin Ge, MD Key Facts Terminology Rapidly growing medullary tumor associated almost exclusively with sickle cell trait Clinical Issues Predominantly young black males Very aggressive; mean survival:…

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Thymic Carcinoma

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Thymic Carcinoma

Thymic Carcinoma Ming Guo, MD Key Facts Clinical Issues High-grade malignancy with poor prognosis Usual sites of metastases include lymph nodes, bone, lung, pleura, liver, and brain Cytopathology Presence of…

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Thymoma

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Thymoma

Thymoma Ming Guo, MD Key Facts Cytopathology Biphasic pattern of epithelial cells and small lymphocytes Epithelioid &/or spindle cells T cells with thymic cortical immunophenotype Ancillary Tests Immunohistochemistry Expression of…

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