Superficial Acral Fibromyxoma



Superficial Acral Fibromyxoma


Thomas Mentzel, MD





Key Facts


Terminology



  • Benign fibroblastic neoplasm with predilection for hands and feet


Clinical Issues



  • Rare tumor


  • Dermal &/or subcutaneous neoplasm


  • Mainly adults


  • Biologically benign neoplasm with recurrences, but no metastases


Microscopic Pathology



  • Dermal neoplasms with involvement of deeper structures in some cases


  • Loose storiform &/or fascicular growth pattern


  • Rare infiltrative growth


  • Spindled and stellate fibroblast-like cells


  • Minimal cytologic atypia and rare mitoses


  • Scattered inflammatory cells (mast cells)


  • CD34 and EMA often positive







Hematoxylin & eosin at scanning magnification shows a hypocellular dermal-based myxoid neoplasm in the nail bed region.






High magnification of superficial acral fibromyxoma shows a predominantly myxoid spindle cell neoplasm with variable cellularity.


TERMINOLOGY


Abbreviations



  • Superficial acral fibromyxoma (SAF)


Definitions



  • Benign fibroblastic neoplasm with predilection for hands and feet, especially nail bed region


ETIOLOGY/PATHOGENESIS


Environmental Exposure



  • Previous trauma reported only rarely


CLINICAL ISSUES


Epidemiology



  • Incidence



    • Rare


  • Age



    • Mainly adults


Presentation



  • Solitary mass


  • Usually painless lesion


Treatment



  • Surgical approaches



    • Complete excision

Tags:
Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Superficial Acral Fibromyxoma

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