Protocol for Urinary Bladder Cancer Specimens



Protocol for Urinary Bladder Cancer Specimens


































































































































































































































Urinary Bladder: Biopsy and Transurethral Resection of Bladder Tumor (TURBT)


Surgical Pathology Cancer Case Summary (Checklist)



Applies primarily to invasive carcinomas &/or associated epithelial lesions, including carcinoma in situ


*Procedure



*____ Biopsy



____ TURBT



*____ Other (specify): ______________________________


Histologic Type



____ Urothelial (transitional cell) carcinoma



____ Urothelial (transitional cell) carcinoma with squamous differentiation



____ Urothelial (transitional cell) carcinoma with glandular differentiation



____ Urothelial (transitional cell) carcinoma with variant histology (specify): ______________________________



____ Squamous cell carcinoma, typical



____ Squamous cell carcinoma, variant histology (specify): ______________________________



____ Adenocarcinoma, typical



____ Adenocarcinoma, variant histology (specify): ______________________________



____ Small cell carcinoma



____ Undifferentiated carcinoma (specify): ______________________________



____ Mixed cell type (specify): ______________________________



____ Other (specify): ______________________________



____ Carcinoma, type cannot be determined


Associated Epithelial Lesions (select all that apply)



____ None identified



____ Urothelial (transitional cell) papilloma (World Health Organization [WHO] 2004/International Society of Urologic Pathology [ISUP])



____ Urothelial (transitional cell) papilloma, inverted type



____ Papillary urothelial (transitional cell) neoplasm, low malignant potential (WHO 2004/ISUP)



____ Cannot be determined


Histologic Grade



____ Not applicable



____ Cannot be determined



Urothelial carcinoma (WHO 2004/ISUP)




____ Low grade




____ High grade




____ Other (specify): ______________________________



Adenocarcinoma and squamous cell carcinoma




____ GX: Cannot be assessed




____ G1: Well differentiated




____ G2: Moderately differentiated




____ G3: Poorly differentiated




____ Other (specify): ______________________________


*Tumor Configuration (select all that apply)



*____ Papillary



*____ Solid/nodule



*____ Flat



*____ Ulcerated



*____ Indeterminate



*____ Other (specify): ______________________________


Adequacy of Material for Determining Muscularis Propria Invasion



____ Muscularis propria (detrusor muscle) not identified



____ Muscularis propria (detrusor muscle) present



____ Presence of muscularis propria indeterminate


Lymph-Vascular Invasion



____ Not identified



____ Present



____ Indeterminate


Microscopic Extent of Tumor (select all that apply)



____ Cannot be assessed



____ Noninvasive papillary carcinoma



____ Flat carcinoma in situ



____ Tumor invades subepithelial connective tissue (lamina propria)



____ Tumor invades muscularis propria (detrusor muscle)



____ Urothelial carcinoma involving prostatic urethra in prostatic chips sampled by TURBT



____ Urothelial carcinoma in situ involving prostatic ducts and acini in prostatic chips sampled by TURBT



____ Urothelial carcinoma invasive into prostatic stroma in prostatic chips sampled by TURBT


*Additional Pathologic Findings (select all that apply)



*____ Urothelial dysplasia (low-grade intraurothelial neoplasia)



*____ Inflammation/regenerative changes



*____ Therapy-related changes



*____ Cautery artifact



*____ Cystitis cystica glandularis



*____ Keratinizing squamous metaplasia



*____ Intestinal metaplasia



*____ Other (specify): ______________________________



* Data elements with asterisks are not required. However, these elements may be clinically important but are not yet validated or regularly used in patient management. Adapted with permission from College of American Pathologists, “Protocol for the Examination of Specimens from Patients with Carcinoma of the Urinary Bladder.” Web posting date October 2009, www.cap.org.



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Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Protocol for Urinary Bladder Cancer Specimens

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