Cystic areas resembling infundibulum with stratified squamous epithelium, granular layer, and basket-weave stratum corneum
Areas resembling internal and external root sheath
Foci of matrical epithelium
Areas resembling hair bulb with papillary mesenchymal bodies
Top Differential Diagnoses
•
Trichoblastoma
Less organized
Lacks more advanced follicular differentiation
Lacks areas resembling infundibulum
Usually composed entirely of basaloid epithelium
•
Trichoepithelioma
Less organized
Also lacks more advanced follicular differentiation
Lacks areas resembling infundibulum
Usually composed entirely of basaloid epithelium
•
Pilomatrixoma
Less organized
Consists only of matrical epithelium and ghost cells
Lacks papillary mesenchymal bodies
Lacks areas resembling infundibulum
Frequent associated granulomatous inflammation
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Trichofolliculoma
Multiple secondary follicles connecting to large, central, cystically dilated follicular structure
Sebaceous glands often present
Panfolliculoma lacks central cystic structure
Sebaceous glands absent in panfolliculoma
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