Osteoma Cutis



Osteoma Cutis


David S. Cassarino, MD, PhD









Low-magnification image of an osteoma cutis shows mature bone-forming trabeculae, with cement lines image surrounding adipocytes and small blood vessels.






Higher power view shows mature trabeculae composed of lamellar-type bone lined by scattered osteoclasts image.


TERMINOLOGY


Synonyms



  • Primary cutaneous osteoma cutis


  • Metaplastic (secondary) ossification


  • Cutaneous ossification


Definitions



  • Primary or secondary cutaneous bone formation


ETIOLOGY/PATHOGENESIS


Primary



  • Often genetic or developmental in origin, presents at early age


  • May be part of Albright hereditary osteodystrophy or other genetic syndromes



    • Albright: X-linked dominant condition associated with characteristic facies, mental retardation, basal ganglia calcification, and cataracts


    • Other rare syndromes include congenital plaquelike osteomatosis, multiple miliary osteomas of face, progressive osseous heteroplasia, and fibrodysplasia ossificans progressiva


Secondary

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Osteoma Cutis

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