Nasal Glioma
Steven D. Billings, MD
Key Facts
Terminology
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Rare congenital anomaly
Clinical Issues
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Subcutaneous mass
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Bridge of nose most common site
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1/3 are intranasal
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20% associated with communication to frontal lobes
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Mandatory to exclude communication with brain prior to excision
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Nodule or polyp
Microscopic Pathology
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Astrocytes and oligodendrocytes
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Loose fibrillary stroma
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Immunoreactive for GFAP
Ancillary Tests
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Positive for GFAP, S100 protein
TERMINOLOGY
Abbreviations
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Nasal glioma (NG)
Synonyms
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Heterotopic glial tissue
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Glial heterotopia
Definitions
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Rare congenital anomaly
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Heterotopic glial tissue
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“Glioma” is misnomer as nasal glioma is nonneoplastic tissue
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Well-circumscribed round, ovoid, or polypoid mass
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Not locally invasive
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CLINICAL ISSUES
Epidemiology
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Incidence
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Very rare
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Rarely associated with other brain or systemic anomalies
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Age
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Newborns
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Identified at birth or within 1st few years of life
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