Highest risk for coagulopathy in retroperitoneal and intrathoracic tumors, but also seen in association with large cutaneous tumors
Clinical photograph shows a large inguinal tumor in an infant. More superficial tumors typically present as an erythematous or violaceous mass.
Histologic examination at low power of kaposiform hemangioendothelioma demonstrates irregular nodules
of spindled cells in the dermis as well as ectatic vessels at periphery of nodules of spindled cells 
.
In some areas, the spindled tumor cells can have a somewhat swirling growth pattern, imparting a glomeruloid
appearance.
The tumor cells have uniform hyperchromatic spindled nuclei and are arranged in short fascicles with slit-like vascular lumina.
CLINICAL ISSUES
Epidemiology
Presentation
• Painful or painless mass
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