Fibrolipomatous Hamartoma

Fibrolipomatous Hamartoma

Cyril Fisher, MD, DSc, FRCPath

MR of the wrist shows abnormal fat signal image in the stroma between the nerve fascicles (black dots) of an enlarged median nerve.

Hematoxylin & eosin shows accumulation of mature adipose tissue with hypocellular fibrous septa around and between nerve bundles.



  • Fibrolipomatous hamartoma of nerve

  • Lipofibromatous hamartoma of nerve

  • Neural fibrolipoma

  • Neurolipomatosis, lipomatosis of nerve


  • Increased fibrofatty tissue infiltrating and surrounding nerves



  • Age

    • Predominantly in children, including congenital lesions

    • Some cases in young adults up to 30 years of age

    • Rarely in older adults


  • Affects palmar surface of hand, wrist, forearm

  • Median nerve and branches most commonly affected

  • Rarely involves ulnar or radial nerve

  • Involves left arm more often than right arm

  • Very rarely involves sciatic, peroneal, or cranial nerve

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Fibrolipomatous Hamartoma
Premium Wordpress Themes by UFO Themes
%d bloggers like this: