Fibroepithelial Stromal Polyp



Fibroepithelial Stromal Polyp


Marisa R. Nucci, MD





Key Facts


Clinical Issues



  • More common during pregnancy


  • Vulva, vagina, and rarely cervix


  • Local excision


Macroscopic Features



  • Usually < 5 cm


  • Typically polypoid or pedunculated


Microscopic Pathology



  • Central fibrovascular core


  • Variably cellular stroma


  • Stellate and multinucleate stromal cells


  • Cytologic features range from small, bland nuclei with dispersed chromatin to enlarged and hyperchromatic with irregular contours (pseudosarcomatous)







Fibroepithelial stromal polyps are typically polypoid lesions with a variably cellular stroma, central fibrovascular core, and overlying squamous epithelium.






The presence of stellate and multinucleate stromal cells directly beneath the epithelial surface is characteristic of fibroepithelial stromal polyps.


TERMINOLOGY



Abbreviations



  • Fibroepithelial stromal polyp (FSP)


Synonyms



  • Pseudosarcomatous stromal polyp


  • Pseudosarcoma botryoides



Definitions



  • Benign polypoid growth that arises from distinctive subepithelial stroma of distal female genital tract


ETIOLOGY/PATHOGENESIS


Cell of Origin



  • Subepithelial mesenchyme of distal female genital tract




CLINICAL ISSUES


Epidemiology

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Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Fibroepithelial Stromal Polyp

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