Cutaneous müllerian cyst
Eccrine cutaneous ciliated cyst
Etiology/Pathogenesis
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Müllerian (paramesonephric) heterotopia
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Metaplasia of sweat gland epithelium
Clinical Issues
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Cutaneous müllerian cyst: Typically affects limbs of young female patients
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Eccrine cutaneous ciliated cyst: Affects men and women, more variable locations
Microscopic
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Ciliated pseudostratified cuboidal or columnar epithelium
May show apocrine, squamous, and mucinous foci
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Unilocular in most cases (rarely multilocular)
Top Differential Diagnoses
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Bronchogenic cyst
Precordial location
Pseudostratified ciliated cuboidal/columnar epithelium
Adjacent tissue may show lymphoid follicles
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Branchial cleft cyst
Near jaw angle
Stratified squamous epithelium
Adjacent tissue shows prominent lymphoid follicles
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Thyroglossal cyst
Midline neck (moves with swallowing)
Pseudostratified cuboidal/columnar (often ciliated) epithelium
Adjacent tissue often shows thyroid follicles
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Thymic cyst
Anterior neck
Squamous or ciliated cuboidal/columnar
Adjacent tissue shows thymic remnants