Class Skeletal muscle relaxant, centrally acting Methocarbamol Commonly Prescribed for (FDA approved in bold) Musculoskeletal conditions. (Adjunct to rest and physical therapy for relief of acute pain.) Muscle spasm Methocarbamol…

Class Ergot, migraine preventive Methylergonovine Commonly Prescribed for (FDA approved in bold) Uterine contractions/bleeding after delivery Migraine prophylaxis Cluster headache Methylergonovine How the Drug Works 5-HT2A/B/C receptor antagonist and 5-HT1B/D…

Class Wake-promoting agent Modafinil Commonly Prescribed for (FDA approved in bold) Reducing excessive sleepiness in patients with narcolepsy or shift-work related sleep disorder Reducing excessive sleepiness in patients with obstructive…

Class Antiepileptic drug (AED) Rufinamide Commonly Prescribed for (FDA approved in bold) Lennox-Gastaut syndrome (LGS) (adjunctive for age 4 and older) Partial-onset seizures with and without generalization in adults and…

Class Osmotic diuretic Mannitol Commonly Prescribed for (FDA approved in bold) Reduction of elevated intracranial pressure (ICP) Reduction of elevated intraocular pressure Diuresis (prophylaxis in acute renal failure) Increased excretion…

Class Antiepileptic drug (AED), barbiturate Phenobarbital Commonly Prescribed for (FDA approved in bold) Generalized tonic-clonic, psychomotor, and partial seizures (monotherapy and adjunctive, children and adults) Status epilepticus Seizures resulting from…

Class Immunosuppressant, immunomodulator, monoclonal antibody Rituximab Commonly Prescribed for (FDA approved in bold) B-cell non-Hodgkin lymphoma (NHL) Rheumatoid arthritis Myasthenia gravis (MG) Multiple sclerosis (MS) (relapsing-remitting) Multifocal motor neuropathy Anti-myelin-associated…

Class Antiarrhythmic Mexiletine Commonly Prescribed for (FDA approved in bold) Cardiac arrhythmias Symptomatic myotonia (myotonia congenita, myotonic dystrophy) Pain in peripheral neuropathy Intractable headache Mexiletine How the Drug Works Class…

Class Ergot, migraine preventative Methysergide Commonly Prescribed for (FDA approved in bold) Migraine prophylaxis Cluster headache prophylaxis Diarrhea associated with carcinoid syndrome Methysergide How the Drug Works 5-HT2 and 5-HT1A/B/C…

Class Triptan Sumatriptan, Sumatriptan/Naproxen Commonly Prescribed for (FDA approved in bold) Migraine Cluster headache (injection only) Sumatriptan, Sumatriptan/Naproxen How the Drug Works Selective 5-HT1 receptor agonist, working predominantly at the…