PHARMACY
TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as “Sweet Spots” for Targeted Therapies
Fig. 1 Relationship between water solubility of TIHs and pulmonary target sites. Depending on the water solubility different primary target sites of TIHs in the human respiratory system can be…
Exocrine Pancreas: The Acinar-Ductal Tango in Physiology and Pathophysiology
Fig. 1 The acinar-ductal functional unit. The acinar cells secrete an isotonic NaCl-rich fluid. Cl− enters the acinar cells through basolateral Na+-K+-2Cl− cotransporters, which can operate due to the Ca2+-activated…
Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration
Fig. 1 Fates of cycling cardiomyocytes. Cardiomyocytes that enter the cell cycle have different fates depending on developmental stages per se and environmental cues (e.g. aging, injury, experimental regeneration). This…
Introduction
, Kyle John Wilby2 and Mary H. H. Ensom1 (1) Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada (2) College of Pharmacy, Qatar University, Doha, Qatar Malaria is a major tropical…
Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions
, Kyle John Wilby2 and Mary H. H. Ensom1 (1) Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada (2) College of Pharmacy, Qatar University, Doha, Qatar This chapter summarizes the clinical…
Pharmacology of Recommended Antimalarial Agents
, Kyle John Wilby2 and Mary H. H. Ensom1 (1) Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada (2) College of Pharmacy, Qatar University, Doha, Qatar Currently recommended antimalarial agents consist…
Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials
, Kyle John Wilby2 and Mary H. H. Ensom1 (1) Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada (2) College of Pharmacy, Qatar University, Doha, Qatar This chapter provides details of…
Pharmacokinetic Drug Interactions Affecting Antimalarials
, Kyle John Wilby2 and Mary H. H. Ensom1 (1) Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada (2) College of Pharmacy, Qatar University, Doha, Qatar This chapter provides details of…
Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials
, Kyle John Wilby2 and Mary H. H. Ensom1 (1) Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada (2) College of Pharmacy, Qatar University, Doha, Qatar In this chapter, we describe…
