PATHOLOGY & LABORATORY MEDICINE

Skeletal Muscle

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Skeletal Muscle

Skeletal Muscle Staci Bryson, MD Larissa V. Furtado, MD Key Facts Embryology Skeletal muscle derives from mesoderm Pharyngeal arches give rise to muscles of head Paraxial mesoderm gives rise to…

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Cartilage

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Cartilage

Cartilage Larissa V. Furtado, MD Key Facts Embryology Cartilage arises from condensation of multipotent mesenchymal cells from mesoderm during week 5 Perichondrium arises from the superficial mesenchyme Chondrogenesis 2 patterns…

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Connective Tissue

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Connective Tissue

Connective Tissue Staci Bryson, MD Larissa V. Furtado, MD Key Facts Embryology Connective tissue is derived from paraxial mesoderm Visceral connective tissue is derived from lateral plate mesoderm Paraxial mesoderm…

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Skin

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Skin

Skin Staci Bryson, MD Key Facts Embryology Dermis Originates from somatic mesoderm and dermomyotome population of somites Elastin and collagen fibers produced at week 11 Epidermis Forms from ectoderm Simple…

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Molecular Factors Index

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Molecular Factors Index

Molecular Factors Index Molecular Factors Discussed Gene Gene Location Official Gene Symbol and Name Chapter Term Found ABCB11 2q24 ABCB11; ATP-binding cassette, sub-family B (MDR/TAP), member 11 Biliary Tract/Liver/Pancreas ABF1…

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Pituitary

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Pituitary

Pituitary Vania Nosé, MD, PhD Pituitary Adenoma as Part of Inherited Tumor Syndromes Syndrome Gene Pituitary Pathology Notes MEN1 MEN1 Prolactin-producing adenoma (66%); GH-producing adenoma; nonfunctional adenoma 40% of patients…

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Head and Neck

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Head and Neck

Head and Neck Vania Nosé, MD, PhD Familial Cancer Syndromes With Head and Neck Neoplasms Syndrome Gene Head and Neck Tumor Other Manifestations Dyskeratosis congenita TERT, TERC, DKC1, TINF2; other…

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Breast

Jul 6, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Breast

Breast David G. Hicks, MD Susan C. Lester, MD, PhD Germline Mutations Associated With Increased Risk of Breast Cancer Gene Population Frequency % of Hereditary Cancers Risk by Age 70…

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