Malignant Peripheral Nerve Sheath Tumor Bruce M. Wenig, MD Key Facts Terminology Malignant tumor of peripheral nerves or having differentiation along the lines of various elements of nerve sheath Occurs…

Leiomyosarcoma Bruce M. Wenig, MD Key Facts Terminology LMS: Malignant tumor of smooth muscle Etiology/Pathogenesis May develop following irradiation or cyclophosphamide exposure Appears to arise from vascular structures Link between…

Malignant Mucosal Melanoma Lester D. R. Thompson, MD Key Facts Terminology Neural crest-derived neoplasms originating from melanocytes and demonstrating melanocytic differentiation Clinical Issues Anterior nasal septum > maxillary sinus Overall…

Squamous Cell Carcinoma Bruce M. Wenig, MD Key Facts Terminology Malignant epithelial neoplasm arising from surface epithelium with squamous cell differentiation Etiology/Pathogenesis Associated risk factors include Nickel exposure, exposure to…

Ectopic Pituitary Adenoma Lester D. R. Thompson, MD Key Facts Terminology Benign pituitary gland neoplasm occurring separately from and without involvement of sella turcica (a normal anterior pituitary gland) Clinical…

Glomangiopericytoma (Sinonasal-type Hemangiopericytoma) Lester D. R. Thompson, MD Key Facts Terminology Soft tissue tumor showing perivascular myoid differentiation Clinical Issues Nasal cavity is usually affected in isolation Present with nasal…

Leiomyoma & Smooth Muscle Tumors of Uncertain Malignant Potential Bruce M. Wenig, MD Key Facts Clinical Issues Benign tumor of smooth muscle One of least common mesenchymal tumors in head…

Pleomorphic Adenoma Lester D. R. Thompson, MD Key Facts Terminology Benign, epithelial-derived neoplasm whose cells demonstrate both epithelial and mesenchymal differentiation Macroscopic Features Develop from mucosa of bony or cartilaginous…

Sinonasal Hamartoma Bruce M. Wenig, MD Key Facts Terminology READ hamartoma: Benign acquired nonneoplastic overgrowth of indigenous glands of sinonasal tract and nasopharynx CORE hamartoma: Related to READ hamartoma but…

Sinonasal Inflammatory Polyp Bruce M. Wenig, MD Key Facts Terminology Nonneoplastic inflammatory swellings of the sinonasal mucosa Etiology/Pathogenesis Etiology linked to multiple factors Clinical Issues Most arise from lateral nasal…