Fibromuscular Dysplasia A. Brad Farris, III, MD Key Facts Terminology Nonatherosclerotic, noninflammatory fibrous, and fibromuscular proliferation of artery, typically leading to stenosis Clinical Issues Mostly young and female 60-90% involve…
Introduction to Impediments to Urine Flow Sanjay Jain, MD, PhD This illustration depicts the different causes (urinary tract intrinsic or extrinsic) of impediments to urine flow. The lesions can arise…
Takayasu Arteritis Surya V. Seshan, MD Key Facts Terminology Granulomatous inflammation of aorta and its major branches Etiology/Pathogenesis Cell-mediated immune mechanism Clinical Issues Common in Asia (6/1,000) compared with USA…
Lecithin-Cholesterol Acyl Transferase Deficiency Ami Bhalodia, MD Key Facts Terminology Complete or partial LCAT deficiency Familial LCAT deficiency Fish eye disease Etiology/Pathogenesis Defect in LCAT-mediated cholesterol ester-formation Mutation of LCAT…
Rheumatoid Arthritis Neeraja Kambham, MD Key Facts Etiology/Pathogenesis Predominantly therapy related Tubulointerstitial nephritis and acute renal failure caused by NSAIDs MGN caused by gold salts, penicillamine, and TNF-α antagonists ANCA-related…
Immunotactoid Glomerulopathy Anthony Chang, MD Key Facts Terminology Congo red negative organized glomerular immunoglobulin deposits Clinical Issues Caucasian predilection Nephrotic syndrome, hematuria, and hypocomplementemia Often associated with monoclonal gammopathy or…
Classification of Cystic Diseases Helen Liapis, MD Joseph Gaut, MD, PhD Adult ADPKD kidneys are massively enlarged and contain numerous oval/spherical cysts dispersed throughout the cortex and medulla. Cysts are…
Blastomycosis Anthony Chang, MD Key Facts Etiology/Pathogenesis Blastomyces dermatitidis Endemic to central/southern United States, Canada Reported in Central/South America, Europe, and Africa Ubiquitous dimorphic fungus acquired by inhalation Macroscopic Features…
Lead and Other Heavy Metal Toxins Shane M. Meehan, MBBCh Key Facts Terminology Renal disease due to toxic effects of lead and other metals Etiology/Pathogenesis Principal toxic metals encountered include…
Tubulointerstitial Nephritis with Uveitis A. Brad Farris, III, MD Key Facts Terminology Tubulointerstitial nephritis with uveitis (TINU) Etiology/Pathogenesis Autoimmune, infectious, environmental, and genetic Most likely cause in most cases is…
