Hepatocellular Carcinoma Michael S. Torbenson, MD 28.1 DEFINITIONS AND TERMINOLOGY Hepatocellular carcinoma is defined as a malignant epithelial tumor that (1) originates in the liver, (2) is differentiated toward hepatocytes…
Benign and Malignant Biliary Tumors Murli Krishna, MD 29.1 INTRODUCTION Biliary neoplasms and tumor-like lesions form a diverse group of lesions in the liver, and include tumors with characteristics similar…
Benign Hepatocellular Tumors Dora Lam-Himlin, MD 27.1 FOCAL NODULAR HYPERPLASIA Definition Focal nodular hyperplasia is a benign hyperplastic reactive lesion composed of nodules of hepatocytes separated by fibrotic bands in…
Benign and Malignant Mesenchymal Tumors of the Liver Rondell P. Graham, MBBS Andrew L. Folpe, MD 26.1 INTRODUCTION Mesenchymal tumors of the liver can be challenging because they are not…
Pediatric Liver Tumors Saba Yasir, MBBS 25.1 HEPATOBLASTOMA Definition Hepatoblastomas are malignant epithelial neoplasms that are primary to the liver and show a range of hepatocellular differentiation, recapitulating various stages…
Imaging of Liver Tumors Michael L. Wells, MD Sudhakar K. Venkatesh, MD Radiologic evaluation represents a critical component of liver tumor detection and characterization. After discovery of a liver mass,…
Molecular Genetics of Liver Diseases Rondell P. Graham, MBBS 23.1 INTRODUCTION Molecular techniques are increasingly used in the characterization of diseases and specimens in clinical practice and research. These scientific…
Cytopathology of the Liver Yajue Huang, MD Andrea Jones, MD Michael Rivera, MD 22.1 INTRODUCTION Fine needle aspiration (FNA) is a commonly used approach to determine the nature of a…
Vascular Disorders Lizhi Zhang, MD 21.1 INTRODUCTION The liver has a dual blood supply. The portal vein provides approximately two-thirds of blood flow to the liver, with blood that is…
Transplantation Pathology Roger K. Moreira, MD Douglas A. Simonetto, MD 20.1 OVERVIEW Chronic liver disease is a major cause of morbidity and mortality worldwide. In the United States alone, nearly…
