Primary Melanocytic Neoplasms Elisabeth J. Rushing, MD Key Facts Terminology Spectrum from low-grade melanocytoma to malignant melanoma No consensus grading system Clinical Issues Sites Posterior fossa, spinal cord, supratentorial Prognosis…
Solitary Fibrous Tumor, Hemangiopericytoma Type Elisabeth J. Rushing, MD Key Facts Terminology Now considered part of solitary fibrous tumor (SFT) spectrum (“cellular” or “malignant” SFT), especially at systemic sites Clinical…
CNS Primitive Neuroectodermal Tumors Fausto J. Rodriguez, MD Key Facts Terminology Heterogeneous group of embryonal neoplasms composed of poorly differentiated cells that may express neuronal and glial markers Clinical Issues…
Embryonal Tumor with Abundant Neuropil and True Rosettes Peter C. Burger, MD Key Facts Terminology Relationship to ependymoblastoma debated Clinical Issues Usually < 3 years Intracranial, both supra- and infratentorial…
Peripheral Primitive Neuroectodermal Tumor (Ewing Sarcoma) Fausto J. Rodriguez, MD Key Facts Terminology Unrelated to intraparenchymal CNS PNETs Etiology/Pathogenesis Somatic rearrangements in EWS gene result in fusion transcripts with aberrant…
Gliomatosis Cerebri Peter C. Burger, MD Key Facts Terminology Defined largely by radiologic criteria Infiltrating glioma involving 3 or more lobes or compartments, often bilaterally Astrocytic, most cases; oligodendroglial, occasional…
Protocol for Specimens of Malignant Melanoma of the Skin David Cassarino, MD, PhD Melanoma of the Skin Biopsy, Excision, Reexcision Procedure (select all that apply) ____ Biopsy, shave ____ Biopsy,…
Other Unusual and Rare Variants of Melanoma David Cassarino, MD, PhD Key Facts Terminology Rare variants of melanoma including chondroid and osseous melanoma, myxoid melanoma, rhabdoid melanoma, and balloon cell…
Sinonasal Melanoma Lester D. R. Thompson, MD Key Facts Terminology Neural crest-derived neoplasms originating from melanocytes and demonstrating melanocytic differentiation Clinical Issues Anterior nasal septum > maxillary sinus Overall prognosis…
Desmoplastic Melanoma Soheil Sam Dadras, MD, PhD Olubukola Babalola David Cassarino, MD, PhD Key Facts Terminology Invasive melanoma that often resembles an inflamed scar Clinical Issues Firm skin-colored, tan or…
