Blastic Plasmacytoid Dendritic Cell Neoplasm M. Yadira Hurley Stephen P. Olsen DEFINITION Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a unique myeloid precursor neoplasm that primarily manifests first with cutaneous…
Cutaneous Extramedullary Hematopoiesis András Schaffer DEFINITION Two categories of extramedullary hematopoiesis (EMH) can be distinguished on the basis of pathogenesis, clinical presentation, and histopathology. In the first category, EMH is…
Cutaneous Manifestations of Myeloproliferative Neoplasms Richard Danialan Carlos A. Torres-Cabala INTRODUCTION Myeloproliferative neoplasms (MPNs) are a group of hematopoietic disorders characterized by the clonal proliferation of cells in the myeloid…
Leukemia Cutis/Aleukemic Leukemia Cutis/Myeloid Sarcoma Kari E. Sufficool John L. Frater INTRODUCTION Acute leukemia may present in a variety of extramedullary tissues with or without bone marrow disease. Though rare,…
Cutaneous Involvement by Precursor B- and T-Cell Neoplasms Alejandro A. Gru DEFINITION Acute lymphoblastic leukemias/lymphomas (ALLs) are neoplasms of precursor lymphoid cells (lymphoblasts), committed to the B- or T-cell lineage…
Lymphomatoid Contact Dermatitis Jonathan G. Bonchak Alejandro A. Gru Matthew J. Zirwas DEFINITION Lymphomatoid contact dermatitis (LCD) is a chronic, persistent allergic contact dermatitis that elicits a robust lymphocytic response…
Cutaneous Plasmacytosis M. Yadira Hurley Angela M. Sutton INTRODUCTION Cutaneous plasmacytosis is a rare entity consisting of a dermal infiltration of polyclonal plasma cells, with or without systemic manifestations including…
Lymphoid Proliferations in Association With Viral and Bacterial Infections Priyadharsini Nagarajan INTRODUCTION Host immune response to combat cutaneous infections depends primarily on the type of organism. For example, in case…
Annular Lichenoid Dermatosis of Youth Alejandro A. Gru DEFINITION Annular lichenoid dermatosis of youth (ALDY) is a clinicopathologic entity originally described in children and young patients, which is clinically reminiscent…
Pseudolymphomas at Sites of Vaccination and in Tattoos Priyadharsini Nagarajan INTRODUCTION Introduction of extraneous materials in the form of tattoos and vaccines can induce a cutaneous inflammatory infiltrate that clinically…
