Overview of Malignant Thymic Neoplasms WHO type A thymoma (spindle cell thymoma) shows characteristic cytomorphology of the tumor cells with elongated spindle cells displaying nuclei that contain dispersed chromatin and…
Herpes Simplex Virus Key Facts Terminology Lung infection caused by double-stranded DNA herpes simplex virus-1 Clinical Issues In infants, disease is transmitted by mother during passage of fetus through infected…
Alveolar Microlithiasis Key Facts Terminology Extensive deposition of microliths in alveolar spaces Etiology/Pathogenesis Rare condition of unknown etiology Familial pattern has been observed in some cases Can occur at any…
Alveolar Proteinosis Key Facts Terminology Nonneoplastic condition in which alveoli are filled with proteinaceous material Clinical Issues Presentation Cough Dyspnea Chest pain Fever Treatment Pulmonary lavage Spontaneous remission in some…
Measles Pneumonia Key Facts Etiology/Pathogenesis Causative agent is a single-stranded, enveloped virus of the family Paramyxoviridae, genus Morbillivirus Clinical Issues Exposure in children < 6 years of age usually results…
Schistosomiasis Key Facts Terminology Synonym Bilharziasis Definition Infection caused by Trematoda (flukes) Etiology/Pathogenesis 3 most common types that affect humans are Schistosoma haematobium (urinary tract) Schistosoma mansoni (intestinal tract) Schistosoma…
Pulmonary Amyloidosis Key Facts Terminology Nonneoplastic process characterized by deposition of amorphous proteinaceous material that may involve lung either primarily or secondarily Etiology/Pathogenesis Secondary to Systemic amyloidosis Light chain disease…
Cytomegalovirus Key Facts Clinical Issues One of the most common opportunistic infections in AIDS and organ transplant patients Diagnosis of CMV pneumonia is based on evaluation of lung biopsy or…
Botryomycosis Key Facts Terminology Chronic, purulent, granulomatous bacterial infection Etiology/Pathogenesis Can be caused by different bacterial organisms Clinical Issues Symptoms Ulcers Draining sinuses Fever Chest pain Hemoptysis More common in…
Pneumocystosis Key Facts Terminology Lung infection caused by fungus Pneumocystis jiroveci (formerly P. carinii) Clinical Issues Infantile form (“plasma cell interstitial pneumonia”) affects premature and malnourished infants Adult (sporadic) form…
