Phen-fen Roberto Barrios Timothy C. Allen Phen-fen, a combination of the amphetamine analogs phentermine and fenfluramine, has been used to treat obesity and substance-abuse disorders. Primary pulmonary hypertension has been…

Methotrexate Roberto Barrios Hakan Çermik Methotrexate is a folic acid antagonist that has been used as an antineoplastic and antiinflam-matory drug. Methotrexate pneumonitis is an unpredictable and sometimes life-threatening side…

Lung Pathology in Collagen Vascular Diseases Abida K. Haque Collagen vascular diseases are a group of immunologically mediated diseases, and may be associated with both localized and diffuse pulmonary lesions….

Amiodarone Roberto Barrios Hakan Çermik’s Amiodarone is a frequently used antiarrhythmic drug. It causes lung changes that are largely reversible but which may become permanent over time. Cytologic Features Finely…

Post-Transplant Lymphoproliferative Disorders Anna Sienko Jeffrey L. Jorgensen First recognized in 1968, post-transplantation lymphoproliferative disorders (PTLD) are a heterogeneous group of lymphoid proliferations that have been described in patients status…

Fungus Pulmonary fungal infections may be endemic or opportunistic. The truly pathogenic (endemic) fungi may infect healthy as well as immunocompromised hosts, whereas the opportunistic fungi usually infect immunocompromised hosts…

Lung Pathology in Transplantation of Other Organs Anna Sienko Due to immunosuppressive therapy, the lung is a frequent site of opportunistic infection in organ transplants of all types and is…

Parasites Several parasites may be found in the lungs and associated tissues of humans. Of these, only two infect human lungs by preference: Dirofilaria immitis and Paragonimus sp. The remainder…

Other Lung Transplant-Related Pathology Anna Sienko Drug reactions, variable tissue reactions to rejection, and a host of other findings may be observed in the lungs of lung transplant recipients. Alveolar…

Organizing Pneumonia in the Transplanted Lung Anna Sienko Organizing pneumonia, or bronchiolitis obliterans organizing pneumonia, may result from any of multiple potential causes in lung transplant patients, including causes that…