Cystic Fibrosis Megan K. Dishop Claire Langston Cystic fibrosis is the major cause of severe chronic lung disease in children. It also is the principal reason for lung transplantation in…

Pulmonary Interstitial Glycogenosis Megan K. Dishop Pulmonary interstitial glycogenosis (PIG) is a form of interstitial widening in infant lungs, typically seen below the age of 6 months. This entity was…

Neuroendocrine Cell Hyperplasia of Infancy (Persistent Tachypnea of Infancy) Megan K. Dishop Claire Langston Neuroendocrine cell hyperplasia of infancy (NEHI) is the pathologic correlate of the clinical syndrome persistent tachypnea…

Tissue Heterotopia and Related Abnormalities Megan K. Dishop Claire Langston Although rare, a variety of heterotopic tissues in the lung have been described, including striated muscle, adrenal tissue, thyroid, pancreas,…

Lymphatic Disorders Megan K. Dishop Claire Langston Congenital pulmonary lymphangiectasis is a rare primary disorder that causes respiratory distress in the newborn. In severe cases it may be fatal within…

Complications of Prematurity Megan K. Dishop Claire Langston Hyaline Membrane Disease Hyaline membrane disease, the histologic counterpart of severe respiratory distress syndrome, is the major cause of neonatal respiratory distress…

Congenital Lobar Overinflation Megan K. Dishop Claire Langston Congenital lobar overinflation, often called congenital (or infantile) lobar emphysema, refers to marked enlargement of a lobe due to airspace enlargement. It…

Pulmonary Hyperplasia and Related Disorders Megan K. Dishop Claire Langston Pulmonary hyperplasia refers to abnormal overgrowth of lung parenchyma, reflected by increased number and enlargement of airspaces. It is always…

Congenital Cystic Adenomatoid Malformation, Large Cyst Type Megan K. Dishop Claire Langston The classification of cystic lesions of the lung remains problematic, as attempts at classification based on size of…

Bronchogenic Cyst Megan K. Dishop Claire Langston Bronchogenic cysts are usually solitary unilocular cystic structures filled with either fluid or mucus and are usually attached to the trachea or major…