The Budget
Fig. 7.1 Steps for submitting the NIH budget 7.3 Complying with Federal Cost Principles For a grant to be accepted by the NIH, not only should it be scientifically sound…
Fig. 7.1 Steps for submitting the NIH budget 7.3 Complying with Federal Cost Principles For a grant to be accepted by the NIH, not only should it be scientifically sound…
Fig. 1.1 Members of the clinical trial research team (IRB institutional review board, Co–PI coprincipal investigator) 1.2 Key Members of the Clinical Trial Research Team 1.2.1 Principal Investigator The principal…
Fig. 18.1 (a–f) MRI sequence: (a axial T1, b coronal T1, c coronal enhanced T1 and d sagittal T1) of a 40-year-old woman presenting with classical apoplexy, who suffered sudden…
Fig. 14.1 (a) CT scan shows hemorrhagic PA extending locally to the suprasellar cisterns. (b) Postoperative CT scan after pituitary removal When SAH is secondary to a preexisting intracranial aneurysm,…
Fig. 16.1 An illustrative case of haemorrhagic RCC (Komatsu et al. 2010). A 46-year-old man had a 4-day history of severe headache. Neurological and endocrinological findings were normal. Coronal MR…
Fig. 9.1 Sagittal section of contrast-enhanced MRI scan showing apoplexy within pituitary tumour 9.2 Pathophysiology Pathophysiology of vasospasm following pituitary apoplexy remains unknown. Trans-diaphragmatic rupture of the sellar tumour into…
Symptoms or signs Percentage of patients Headache Up to 100 % Nausea and vomiting 40–70 % Meningeal irritation 25 % Photophobia 33 % Mental deterioration 20 % Ocular paresis (diplopia…
Fig. 10.1 Anatomy of the pituitary fossa and cavernous sinus (Adapted with kind permission from Gray (1918); Bartleby.com, 2000. www.bartleby.com/107) 10.4 Neuro-ophthalmological Signs in Acute Pituitary Apoplexy The literature describing…
Fig. 20.1 Preoperative Contrast MRI of the Brain reveal a sellar surprasellar mass lesion with significant subfrontal extension Lowerate bulging into Sphenoid Sinus: (a) Axial, (b, c) Sagittal and (d)…
Fig. 15.1 Enhanced CT scan on axial view (a) and sagittal T2-weighted MRI (b) showing a bilateral hypothalamic lymphoma with suprasellar extension, optic chiasm infiltration and brainstem involvement Fig. 15.2…