Hematopoietic Neoplasms of Skin in Children
Hematopoietic Neoplasms of Skin in Children Samir B. Kahwash Patricia M. Witman Alejandro A. Gru There are several unique aspects of pediatric tumors in general, and hematopoietic neoplasms in particular,…
Ocular Lymphoproliferative Disorders
Ocular Lymphoproliferative Disorders Juan O. Croxatto Carolina M. Gentile INTRODUCTION The “ocular adnexum” is the comprehensive name for those tissues that sustain and give strength to the globe, including the…
Oral Lymphoproliferative Disorders
Oral Lymphoproliferative Disorders Kristin K. McNamara Carl M. Allen INTRODUCTION Lymphoproliferative diseases (LPDs) that affect the oral region are incredibly diverse. The clinicopathologic spectrum ranges from reactive lymphoid hyperplasia to…
Intralymphatic Histiocytosis and Melkersson–Rosenthal Syndrome
Intralymphatic Histiocytosis and Melkersson–Rosenthal Syndrome Andrea P. Moy Louis P. Dehner Rosalynn M. Nazarian INTRALYMPHATIC HISTIOCYTOSIS Definition Intralymphatic histiocytosis is a rare disorder that is characterized by a proliferation of…
Histiocytic and Dendritic Cell Sarcomas
Histiocytic and Dendritic Cell Sarcomas Archana Shenoy Louis P. Dehner INTRODUCTION The subject of histiocytic lesions of the skin is a topic usually dominated by Langerhans cell histiocytosis and juvenile…
Reticulohistiocytoma and Reticulohistiocytosis
Reticulohistiocytoma and Reticulohistiocytosis Jacob R. Bledsoe Louis P. Dehner Rosalynn M. Nazarian DEFINITION Reticulohistiocytoma (RH) (solitary epithelioid histiocytoma) is a rare cutaneous histiocytic proliferation of unknown etiology that typically presents…
Non-Langerhans Cell Histiocytoses
Non-Langerhans Cell Histiocytoses Andrea P. Moy Louis P. Dehner Rosalynn M. Nazarian JUVENILE AND ADULT XANTHOGRANULOMA Introduction Juvenile and adult xanthogranuloma are benign proliferations of non-Langerhans histiocytes. The juvenile xanthogranuloma…
Rosai–Dorfman Disease
Rosai–Dorfman Disease Joseph R. Kallini M. Yadira Hurley DEFINITION Rosai–Dorfman disease (RDD), also referred to as Destombes–Rosai–Dorfman syndrome, is a benign proliferative disorder of histiocytes. It is also termed sinus…
Benign and Malignant Langerhans Cell Proliferations
Benign and Malignant Langerhans Cell Proliferations Jacob R. Bledsoe Louis P. Dehner Rosalynn M. Nazarian DEFINITION Langerhans cell histiocytosis (LCH) is a clinically heterogeneous disorder characterized by a clonal proliferation…
Mast Cell Neoplasms
Mast Cell Neoplasms Jonathan J. Davick Catherine G. Chung Liaqat Ali MASTOCYTOMA Definition A form of cutaneous mastocytosis characterized by the presence of one or a few solitary cutaneous tumors…
