Fibrohistiocytic tumors of intermediate malignancy originally included only dermatofibrosarcoma protuberans and the closely related giant cell fibroblastoma. This category now embraces other lesions, such as plexiform fibrohistiocytic tumor and soft…
Immunohistochemistry (IHC) is the use of antibody-based reagents for localization of specific epitopes in tissue sections. Over the past several decades, IHC has become a powerful tool to assist the…
Fibrous tumors of infancy and childhood can be divided into two large groups: (1) lesions that correspond to similar lesions in adults in terms of clinical setting, microscopic picture, and…
Over the past several decades, remarkable advances have been seen in the use of imaging for diagnosing, staging, and following up cases of soft tissue neoplasms. In this chapter we…
Acknowledgments An apology is extended to those colleagues whose papers could not be cited because of space considerations. Human neoplasms display a wide variety of genetic alterations, most of which…
Clinical Information The diagnosis of a soft tissue lesion requires a modicum of clinical information and adequate, well-processed tissue. At a minimum, the pathologist should be apprised of patient age,…
Although soft tissue sarcomas are a heterogeneous group of neoplasms, their clinical evaluation and treatment follow common principles. This chapter focuses on the clinical evaluation, determinants of prognosis and outcome,…
Soft tissue can be defined as nonepithelial extraskeletal tissue of the body exclusive of the reticuloendothelial system, glia, and supporting tissue of various parenchymal organs. It is represented by the…
Sex Cord–Stromal Tumors ▪ These tumors (SCSTs), which account for ~5% of all primary ovarian tumors, are classified primarily on the basis of the constituent recognizable cell types ( Table…
General Features of Epithelial Ovarian Tumors Approach to Ovarian Tumor Diagnosis ( Tables 13.1 and 13.2 ) As this is the first chapter considering ovarian tumors, some remarks concerning their…
