Antibody Index



Antibody Index







































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































































Antibodies Discussed


Antibody Name/Symbol


Antibody Description


Clones/Alternative Names


Chapters


α1-antichymotrypsin


alpha 1 antichromotrypsin


A1ACT


Myofibroma and Myofibromatosis; PEComas


α-fetoprotein


alpha 1 fetoprotein


AFP, Z5A06, Clone C3


Metastatic Tumors to the Skin


β-2-microglobulin



B2-microglob


Angioimmunoblastic T-cell Lymphoma; Mycosis Fungoides (and Subtypes)


β-catenin


beta catenin; involved in regulation of cell adhesion and in signal transduction through Wnt pathway


B-catenin, CLONE 14, E-5, RB-9035Po, 17C2, 5H10


Digital Fibromatosis (Infantile Digital Fibromatosis); Ectopic Meningioma; Extranodal NK/T-cell Lymphoma, Nasal Type; Fibromatosis; Fibrosarcoma; Juvenile Hyaline Fibromatosis; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Myofibroma and Myofibromatosis; Pilomatrixoma and Pilomatrical Carcinoma; Plexiform Fibrohistiocytic Tumor; Pseudosarcomatous Fibroblastic Proliferations


34bE12


cytokeratin, high molecular weight (34bE12- CK 1, 5, 10, 14)


MA-903, CK903


Toker Cell Hyperplasia


Actin-HHF-35


actin, muscle (HHF35)


MSA, HHF-35


Angiomatoid Fibrous Histiocytoma; Myofibroma and Myofibromatosis; PEComas; Sinonasal Melanoma


Actin-sm


actin, smooth muscle


SMA, ASM-1, CGA7, 1A4, HUC1-1


Adenoid Cystic Carcinoma; Angioleiomyoma; Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Atypical Fibroxanthoma; Bronchogenic Cyst; Cellular Neurothekeoma; Congenital Smooth Muscle Hamartoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Dermatofibroma and Fibrous Histiocytoma; Digital Fibromatosis (Infantile Digital Fibromatosis); Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Hemangioendothelioma; Epithelioid Sarcoma; Glomus Tumors; Infantile Hemangioma; Kaposi Sarcoma; Leiomyosarcoma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Myxofibrosarcoma; Neuromas; PEComas; Perineurioma; Pleomorphic Fibroma; Pseudosarcomatous Fibroblastic Proliferations; Sinonasal Melanoma; Spindle Cell Hemangioma; Squamous Cell Carcinoma (and Variants)


Adipophilin


ADFP (adipose differentiationrelated protein)


AP125


Hidradenocarcinoma; Hidradenoma


AE1/AE3


mixture of 2 anticytokeratin clones that detect a variety of both high and low molecular weight cytokeratins



Atypical Fibroxanthoma; Congenital Smooth Muscle Hamartoma; Digital Fibromatosis (Infantile Digital Fibromatosis); Epithelioid Sarcoma; Extramammary Paget Disease; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Median Raphe Cyst; Squamomelanocytic Tumor; Syringocystadenoma Papilliferum


ALK


anaplastic lymphoma kinase 1


ALK1, 5A4, ALKC


Atypical Lipomatous Tumor and Liposarcoma; Histiocytic Sarcoma; Lymphomatoid Papulosis; Primary Cutaneous Anaplastic Large Cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


ALK1


anaplastic lymphoma kinase 1


5A4, ALKC


Adult T-cell Leukemia/Lymphoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Primary Cutaneous Anaplastic Large Cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


Androgen receptor



AR441, F39.4.1, AR-N20, ANDROGEN RE


Apocrine Carcinoma (Apocrine Adenocarcinoma); Basal Cell Carcinoma; Hidradenoma; Sebaceous Carcinoma; Squamous Cell Carcinoma (and Variants); Squamous Cell Carcinoma In Situ (Bowen Disease); Tricholemmal Carcinoma


APC


adenomatous polyposis coliprotein



Fibromatosis; Myofibroma and Myofibromatosis


BAD


Bcl-2-associated agonist of cell death



Mucosal Melanoma (Genital)


BAX


Bcl-2-associated X protein


PU-347-P, B-9, BAX-P, P19, BAX-M


Basal Cell Carcinoma


Bcl-1



Cyclin-D1


Systemic B-cell Lymphomas Involving the Skin


Bcl-2


B-cell lymphoma 2; suppresses apoptosis in a variety of cell systems


ONCL2, BCL2/100/D5, 124, 124.3


Actinic Keratosis; Basal Cell Carcinoma; Cutaneous Marginal Zone B-cell Lymphoma; Diffuse Large B-cell Lymphoma, Leg Type; Digital Fibromatosis (Infantile Digital Fibromatosis); Inverted Follicular Keratosis; Leukemia Cutis; Lymphomatoid Papulosis; Microcystic Adnexal Carcinoma; Nevus Sebaceus and Follicular Hamartomas; Perineurioma; Primary Cutaneous Follicle Center Lymphoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sebaceous Carcinoma; Systemic B-cell Lymphomas Involving the Skin; Trichoblastoma; Trichoepithelioma


Bcl-6


B-cell CLL/lymphoma 6


LN22, GI191E/A8, N-3, PG-B6P, P1F6, 3FR-1


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Marginal Zone B-cell Lymphoma; Diffuse Large B-cell Lymphoma, Leg Type; Leukemia Cutis; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma


BDCA-2


monoclonal antibody directed toward immature plasmacytoid dendritic cells


CD303


Blastic Plasmacytoid Dendritic Cell Neoplasm


BER-EP4


epithelial cell adhesion molecule


AUA1, VU-1D9, EPCAM, C10, HEA125


Actinic Keratosis; Basal Cell Carcinoma; Hidradenocarcinoma; Hidradenoma; Metastatic Tumors to the Skin; Sebaceoma (Sebaceous Epithelioma); Sebaceous Adenoma; Sebaceous Carcinoma; Squamous Cell Carcinoma (and Variants)


BF1


T-cell receptor antigen


T_Cell_AG_R, Beta-F1, 8A3, TCR


Intravascular Large B-cell Lymphoma


BMI1


B-cell-specific Moloney murine leukemia virus site 1


6C9, F6


Basal Cell Carcinoma


BOB.1


B-cell OCT-binding protein 1


SC955, BOB1


Lymphomatoid Granulomatosis


C-Kit


tyrosine-protein kinase activity


CD117, C-19 (C-KIT), 104D2, 2E4, CKIT, A4502, H300, CMA-767


Cutaneous and Systemic Mastocytosis


c-myc


myelocytomatosis viral oncogene


C-MYC, 9E10, 9E11, 1-262


Atypical Vascular Lesion; Systemic B-cell Lymphomas Involving the Skin


C-reactive protein


Acute phase protein involved in complement activation


CRP


Extranodal NK/T-cell Lymphoma, Nasal Type; Subcutaneous Panniculitis-like T-cell Lymphoma


CA 19-9


related to the Lewis blood group; shown to label multiple types of adenocarcinomas


1116NS19-9


Metastatic Tumors to the Skin


Calcitonin


polypeptide hormone produced by parafollicular cells (C cells) of the thyroid


CALBINDIN28


Metastatic Tumors to the Skin


Caldesmon


actin interacting and calmodulin binding protein found in smooth muscle and other cell types



Digital Fibromatosis (Infantile Digital Fibromatosis); Glomus Tumors; Leiomyosarcoma; Myofibroma and Myofibromatosis; Pseudosarcomatous Fibroblastic Proliferations


Calponin


thin filament-associated protein that is implicated in regulation and modulation of smooth muscle contraction


N3, 26A11, CALP, CNN1, SMCC, Sm Calp


Adenoid Cystic Carcinoma; Angiomatoid Fibrous Histiocytoma; Chondroid Lipoma; Cutaneous Mixed Tumor (Chondroid Syringoma); Cylindroma; Digital Fibromatosis (Infantile Digital Fibromatosis); Fibromatosis; Leiomyoma (Pilar); Leiomyosarcoma; Malignant Mixed Tumor; Myofibroma and Myofibromatosis; PEComas; Pseudosarcomatous Fibroblastic Proliferations; Spiradenoma


Calretinin


29 kDa calcium binding protein that is expressed in central and peripheral nervous system and in many normal and pathological tissues


DAK-CALRET, 5A5, CAL 3F5, DC8, AB149


Granular Cell Tumor; Metastatic Tumors to the Skin


Carcinooembryonic antigen



CEA-M, mCEA, CEA-B18, CEA-D14, CEAGOLD 1, T84.6, CEA-GOLD 2, CEA 11, CEA-GOLD 3, CEA 27, CEAGOLD 4, CEA 41, CEA-GOLD 5, T84.1, CEA-M, A5B7, CEJ065, IL-7, T84.66, TF3H8-1, 0062, D14, alpha-7, PARLAM 1, ZC23, CEM010, A115, COL-1, AF4, 12.140.10, 11-7, M773, CEA-M431_31, CEJO65


Clear Cell Papulosis; Cutaneous Mixed Tumor (Chondroid Syringoma); Papillary Eccrine Adenoma


CCND1


protein with important cell cycle regulatory functions


Cyclin-D1, bcl-1 (cyclin D1) A-12, PRAD1, AM29, DCS-6, SP4, 5D4, D1GM, P2D11F11, CCND1, Cyl-1


Systemic B-cell Lymphomas Involving the Skin


CCR4


chemokine receptor 4


CD194


Leukemia Cutis


CD1a


T-cell surface glycoprotein


JPM30, CD1A, O10, NA1/34


Blastic Plasmacytoid Dendritic Cell Neoplasm; Histiocytic Sarcoma; Juvenile and Adult-type Xanthogranuloma; Langerhans Cell Histiocytosis; Leukemia Cutis; Multicentric Reticulohistiocytosis; Non-Langerhans Cell Histiocytoses; Polyvinylpyrrolidone Storage Disease; Reticulohistiocytoma; Rosai-Dorfman Disease


CD2


T-cell surface antigen


271, MT910, AB75, LFA-2


Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous and Systemic Mastocytosis; Cutaneous Gamma-Delta T-cell Lymphoma; Histiocytic Sarcoma; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD3


T-cell receptor


F7238, A0452, CD3-P, CD3-M, SP7, PS1


Adult T-cell Leukemia/Lymphoma; Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Angiosarcoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Cutaneous Marginal Zone B-cell Lymphoma; Extramammary Paget Disease; Extranodal NK/T-cell Lymphoma, Nasal Type; Histiocytic Sarcoma; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Lymphomatoid Granulomatosis; Lymphomatoid Papulosis; Non-Langerhans Cell Histiocytoses; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma; Reticulohistiocytoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD3-ε


T-cell surface antigen T3/Leu-4 epsilon chain


CD3E, CD3e


Extranodal NK/T-cell Lymphoma, Nasal Type


CD4


T-cell surface glycoprotein L3T4


IF6, 1290, 4B12, CD4


Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Extramammary Paget Disease; Histiocytic Sarcoma; Leukemia Cutis; Lymphomatoid Granulomatosis; Lymphomatoid Papulosis; Mycosis Fungoides (and Subtypes); Non-Langerhans Cell Histiocytoses; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD5


T-cell surface glycoprotein Leu1, T1


NCL-CD5, 4C7, 54/B4, 54/F6


Adult T-cell Leukemia/Lymphoma; Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Cutaneous Gamma-Delta T-cell Lymphoma; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic B-cell Lymphomas Involving the Skin; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD7


T-cell antigen precursor Leu 9


272, CD7-272


Adult T-cell Leukemia/Lymphoma; Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Intravascular large B-cell Lymphoma; Leukemia Cutis; Lymphomatoid Granulomatosis; Lymphomatoid Papulosis; Mycosis Fungoides (and Subtypes); Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD8


T-cell coreceptor antigen Leu 2, T-cytotoxic cells


M7103, C8/144, C8/144B


Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Cutaneous Gamma-Delta T-cell Lymphoma; Extramammary Paget Disease; Extranodal NK/T-cell Lymphoma, Nasal Type; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Lymphomatoid Papulosis; Mycosis Fungoides (and Subtypes); Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD9


motility-related protein-1 (MRP-1)


72F16, BA-2


Cutaneous and Systemic Mastocytosis


CD10


neutral endopeptidase


NCL-270, CALLA, neprilysin, neutral endopeptidase, NEP


Adult T-cell Leukemia/Lymphoma; Angioimmunoblastic T-cell Lymphoma; Atypical Fibroxanthoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Marginal Zone B-cell Lymphoma; Cutaneous Plasmacytoma; Dermatofibroma and Fibrous Histiocytoma; Dermatofibrosarcoma Protuberans; Diffuse Large B-cell Lymphoma, Leg Type; Hidradenocarcinoma; Hidradenoma; Leiomyosarcoma; Leukemia Cutis; Metastatic Tumors to the Skin; PEComas; Pleomorphic Fibroma; Primary Cutaneous Follicle Center Lymphoma; Sebaceous Carcinoma; Squamous Cell Carcinoma (and Variants); Systemic B-cell Lymphomas Involving the Skin; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD13


plays role in growth of DC/macrophage progenitors and precursors



Extramedullary Hematopoiesis; Histiocytic Sarcoma


CD14


coreceptor for lipopolysaccharide binding protein


FMC32


Cutaneous and Systemic Mastocytosis; Histiocytic Sarcoma; Non-Langerhans Cell Histiocytoses


CD15


reacts with Reed-Sternberg cells of Hodgkin lymphoma and with granulocytes


VIM-2,3C4, LEU-M1, TU9, VIM-D5, MY1, CBD1, MMA, 3CD1, C3D1, Lewis x, SSEA-1


Cutaneous and Systemic Mastocytosis; Extramedullary Hematopoiesis; Histiocytic Sarcoma; Langerhans Cell Histiocytosis; Lymphomatoid Papulosis; Myxoinflammatory Fibroblastic Sarcoma; Systemic B-cell Lymphomas Involving the Skin


CD16


Fc receptor of IgG found on the surfaces of natural killer cells, neutrophils, monocytes, and macrophages



Cutaneous and Systemic Mastocytosis; Intravascular Large B-cell Lymphoma


CD19


B-cell antigen



Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Marginal Zone B-cell Lymphoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Intravascular large B-cell Lymphoma; Leukemia Cutis; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma; Systemic B-cell Lymphomas Involving the Skin


CD20


activated-glycosylated phosphoprotein expressed on the surface of B cells from late pro-B cells through memory B cells


FB1, B1, L26


Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Cutaneous Plasmacytoma; Diffuse Large B-cell Lymphoma, Leg Type; Extranodal NK/T-cell Lymphoma, Nasal Type; Histiocytic Sarcoma; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Lymphomatoid Granulomatosis; Lymphomatoid Papulosis; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma; Reticulohistiocytoma; Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic B-cell Lymphomas Involving the Skin; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD21


CR2, complement component receptor 2, Epstein-Barr virus receptor



Adult T-cell Leukemia/Lymphoma; Angioimmunoblastic T-cell Lymphoma; Cutaneous Marginal Zone B-cell Lymphoma; Cutaneous Plasmacytoma; Diffuse Large B-cell Lymphoma, Leg Type; Histiocytic Sarcoma; Primary Cutaneous Follicle Center Lymphoma; Rosai-Dorfman Disease; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD22


B-cell receptor


FPC1, LEU 14


Cutaneous Marginal Zone B-cell Lymphoma; Intravascular Large B-cell Lymphoma


CD23


Fc ε RII, low-affinity IgE receptor, IGEBF


1B12, MHM6BU38


Angioimmunoblastic T-cell Lymphoma; Cutaneous Marginal Zone B-cell Lymphoma; Diffuse Large B-cell Lymphoma, Leg Type; Histiocytic Sarcoma; Leukemia Cutis; Primary Cutaneous Follicle Center Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD25


IL-2 receptor alpha


2A3, 4C9


Adult T-cell Leukemia/Lymphoma; Cutaneous and Systemic Mastocytosis; Leukemia Cutis; Lymphomatoid Papulosis; Mycosis Fungoides (and Subtypes)


CD26


ADA adenosine deaminase complexing protein 2, DPP4


44-4


Leukemia Cutis; Mycosis Fungoides (and Subtypes)


CD29


fibronectin receptor, integrein beta 1


ITGB1, 29C03, 7F10, HT29_12938


Intravascular Large B-cell Lymphoma


CD30


tumor necrosis factor SF8


BER-H2, KI-1, TNFRSF8


Adult T-cell Leukemia/Lymphoma; Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Histiocytic Sarcoma; Leukemia Cutis; Lymphomatoid Papulosis; Mycosis Fungoides (and Subtypes); Myxoinflammatory Fibroblastic Sarcoma; Primary Cutaneous Anaplastic Large Cell Lymphoma; Systemic B-cell Lymphomas Involving the Skin; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD31


platelet endothelial cell adhesion molecule


JC/70, JC/70A, PECAM-1


Angiolymphoid Hyperplasia with Eosinophilia; Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Atypical Fibroxanthoma; Dermal Nerve Sheath Myxoma; Dermatofibroma and Fibrous Histiocytoma; Epithelioid Hemangioendothelioma; Epithelioid Sarcoma; Infantile Hemangioma; Kaposi Sarcoma; Kaposiform Hemangioendothelioma; Lymphangioma and Superficial Lymphangioma; Melanoma, Superficial Spreading Type; Multinucleate Cell Angiohistiocytoma; Papillary Intralymphatic Angioendothelioma (Dabska Tumor); Progressive Lymphangioma; Pseudosarcomatous Fibroblastic Proliferations; Retiform Hemangioendothelioma; Spindle Cell and Pleomorphic Lipoma; Superficial Malignant Peripheral Nerve Sheath Tumor; Vascular Hamartomas


CD33


SIGLEC lectin 3


PWS44


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous and Systemic Mastocytosis; Extramedullary Hematopoiesis; Histiocytic Sarcoma; Leukemia Cutis


CD34


hematopoietic progenitor cell antigen


MY10, IOM34, QBEND10, 8G12, 1309, HPCA-1, NU-4A1, TUK4, clone 581, BI-3c5


Acral Fibrokeratoma; Angiofibroma and Related Lesions; Angioleiomyoma; Angiolymphoid Hyperplasia with Eosinophilia; Angiomatoid Fibrous Histiocytoma; Angiomyofibroblastoma; Angiosarcoma; Atypical Fibroxanthoma; Atypical Lipomatous Tumor and Liposarcoma; Childhood Melanoma; Collagenous Fibroma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Dermal Nerve Sheath Myxoma; Dermatofibroma and Fibrous Histiocytoma; Dermatofibrosarcoma Protuberans; Dermatomyofibroma; Digital Fibromatosis (Infantile Digital Fibromatosis); Distinctive Dermal Clear Cell Mesenchymal Tumor; Eccrine Hamartomas; Ectopic Meningioma; Epithelioid Hemangioendothelioma; Epithelioid Histiocytoma; Epithelioid Sarcoma; Extramedullary Hematopoiesis; Fibromatosis; Fibrosarcoma; Fibrous Hamartoma of Infancy; Glomus Tumors; Granular Cell Tumor; Hibernoma; Infantile Hemangioma; Kaposi Sarcoma; Kaposiform Hemangioendothelioma; Leiomyosarcoma; Leukemia Cutis; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Lymphangioma and Superficial Lymphangioma; Multinucleate Cell Angiohistiocytoma; Myofibroma and Myofibromatosis; Myxofibrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Neurofibroma; Neuromas; Nevus Sebaceus and Follicular Hamartomas; Non-Langerhans Cell Histiocytoses; Papillary Intralymphatic Angioendothelioma (Dabska Tumor); Perineurioma; Pleomorphic Fibroma; Plexiform Fibrohistiocytic Tumor; Progressive Lymphangioma; Pseudosarcomatous Fibroblastic Proliferations; Reticulohistiocytoma; Retiform Hemangioendothelioma; Sclerotic Fibroma; Spindle Cell and Pleomorphic Lipoma; Spindle Cell Hemangioma; Superficial Acral Fibromyxoma; Verrucous Hemangioma


CD35


erythrocyte complement receptor 1, CR1, immune adherence receptor, C3b/C4b receptor


BER-MAC-DRC, TO5, CD35, E11


Angioimmunoblastic T-cell Lymphoma; Diffuse Large B-cell Lymphoma, Leg Type; Histiocytic Sarcoma; Primary Cutaneous Follicle Center Lymphoma; Rosai-Dorfman Disease; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CD43


Major sialoglycoprotein on surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes


LEU-22, DF-T1, L60, MT1, sialophorin, leukosialin, SPN


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Marginal Zone B-cell Lymphoma; Extramedullary Hematopoiesis; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Primary Cutaneous Follicle Center Lymphoma; Systemic B-cell Lymphomas Involving the Skin


CD44


cell adhesion receptor for hyaluronic acid


HCAM, CD44H, B-F24, A3D8, 2C5, CD44S, F10-44.2, 156-3C11, DF1485, BBA10, VFF-14, CD44V10, CD44V3, 3G5, CD44V3-10-P, CD44V3-10, 3D2, CD44V4_5, CD44V5,VFF-8, VFF-7, 2F10, VFF-18, CD44V6, CD44V7, VFF-9, CD44V7_8, VFF-17


Primary Neuroendocrine (Merkel Cell) Carcinoma


CD45


leukocyte common antigen


LCA, PD7/26, 1.22/4.14, T29/33, RP2/18, PD7, 2D1, 2B11+PD7/26


Angiomatoid Fibrous Histiocytoma; Cutaneous and Systemic Mastocytosis; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Extramammary Paget Disease; Giant Cell Tumor of Tendon Sheath; Leukemia Cutis; Multicentric Reticulohistiocytosis; Myxoinflammatory Fibroblastic Sarcoma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Primary Neuroendocrine (Merkel Cell) Carcinoma; Spiradenoma; Extramammary Paget Disease; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


CD45RA


isoform of CD45 expressed by naive T cells


4KB5, MT2, CD45RA, MB1


Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia Cutis


CD45RB


isoform of CD45 expressed by naive and memory T cells



Extramedullary Hematopoiesis; Non-Langerhans Cell Histiocytoses; Oral Melanoma; Sinonasal Melanoma


CD45RO


isoform of CD45 located on memory T cells


ICH1-L, low molecular weight isoform LCA


Leukemia Cutis


CD54


ICAM-1 (intracellular adhesion molecule 1)


23G12, CD54-P, ICAM


Intravascular Large B-cell Lymphoma


CD56


NCAM (neutral cellular adhesion molecule)


MAB735, ERIC-1, 25-KD11, 123C3, 24-MB2, BC56C04, 1B6, 14-MAB735, NCC-LU-243, MOC-1, NCAM


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Lymphomatoid Granulomatosis; Lymphomatoid Papulosis; Neuromas; Sinonasal Melanoma; Subcutaneous Panniculitis-like T-cell Lymphoma


CD57


β-1,3-glucuronyl transferase 1 (glucuronosyl transferase P)


LEU-7, NK1, HNK-1, TB01, B3GAT1


Granular Cell Tumor; Intravascular Large B-cell Lymphoma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Schwannoma (Neurilemmoma)


CD61


cluster of differentiation found on thrombocytes corresponding to glycoprotein IIb/IIIa


Integrin, beta 3 (platelet glycoprotein IIIa), ITGB3, GP3A, GPIIIa, Y2/5, HPA


Extramedullary Hematopoiesis


CD63


tetraspan intracellular granule protein


NKI/C3, basophil activation test in allergy


Cellular Neurothekeoma; Plexiform Fibrohistiocytic Tumor


CD64


Fc receptor for IgG antibodies, high affinity


HAM56


Reticulohistiocytoma


CD68


cytoplasmic granule protein of monocytes, macrophages


PG-M1, KP-1, LN5


Angiofibroma and Related Lesions; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Atypical Lipomatous Tumor and Liposarcoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cellular Neurothekeoma; Chondroid Lipoma; Cutaneous and Systemic Mastocytosis; Dermal Nerve Sheath Myxoma; Dermatofibroma and Fibrous Histiocytoma; Dermatofibrosarcoma Protuberans; Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Histiocytoma; Giant Cell Tumor of Tendon Sheath; Granular Cell Tumor; Histiocytic Sarcoma; Juvenile and Adult-type Xanthogranuloma; Langerhans Cell Histiocytosis; Leiomyosarcoma; Leukemia Cutis; Multicentric Reticulohistiocytosis; Multinucleate Cell Angiohistiocytoma; Myxoinflammatory Fibroblastic Sarcoma; Non-Langerhans Cell Histiocytoses; Pleomorphic Fibroma; Plexiform Fibrohistiocytic Tumor; Polyvinylpyrrolidone Storage Disease; Pseudosarcomatous Fibroblastic Proliferations; Reticulohistiocytoma; Rosai-Dorfman Disease; Squamous Cell Carcinoma (and Variants)


CD79a


immunoglobulin-associated alpha, MB1


MB-1, 11D10, 11E3, CD79A, HM47/A9, HM57, JCB117, CD79-a, CD79-α


Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Marginal Zone B-cell Lymphoma; Intravascular large B-cell Lymphoma; Leukemia Cutis; Lymphomatoid Granulomatosis; Primary Cutaneous Follicle Center Lymphoma; Sinonasal Melanoma


CD99


cell surface glycoprotein for migration, T-cell adhesion, MIC2


CD99-MEMB, 12E7, HBA71, O13, P30/32MIC2, M3601


Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Cutaneous Rhabdomyosarcoma; Digital Fibromatosis (Infantile Digital Fibromatosis); Epithelioid Sarcoma; Leiomyosarcoma; Leukemia Cutis; Metastatic Tumors to the Skin; Perineurioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Pleomorphic Fibroma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sinonasal Melanoma; Squamous Cell Carcinoma (and Variants)


CD117


C-Kit, tyrosine-protein kinase activity


C-19 (C-KIT), 104D2, 2E4, C-KIT, A4502, H300, CMA-767


Angiosarcoma; Cutaneous and Systemic Mastocytosis; Cutaneous Plasmacytoma; Fibromatosis; Leukemia Cutis; Myxoinflammatory Fibroblastic Sarcoma; Oral Melanoma; PEComas; Sinonasal Melanoma


CD123


receptor for IL-3 (IL-3R)



Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia Cutis


CD138


syndecan; a useful marker for plasma cells


B-B4, AM411-10M, MI15


Cutaneous Plasmacytoma; Sinonasal Melanoma; Systemic B-cell Lymphomas Involving the Skin


CD163


macrophage hemoglobin scavenging system


10D6


Dermatofibroma and Fibrous Histiocytoma; Dermatofibrosarcoma Protuberans; Histiocytic Sarcoma; Myxoinflammatory Fibroblastic Sarcoma; Non-Langerhans Cell Histiocytoses; Plexiform Fibrohistiocytic Tumor; Polyvinylpyrrolidone Storage Disease; Reticulohistiocytoma


CD303


monoclonal antibody directed toward immature plasmacytoid dendritic cells


BDCA-2


Leukemia Cutis


CDK4


cyclin dependant kinase 4


C-22, DCS-31


Atypical Lipomatous Tumor and Liposarcoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Hibernoma; PEComas; Spindle Cell and Pleomorphic Lipoma


CDX-2


caudal type homeobox transcription factor 2


AMT28, 7C7/D4, CDX-2-88


Extramammary Paget Disease; Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Metastatic Tumors to the Skin; Primary Cutaneous Mucinous Carcinoma


CEA-M


carcinoembryonic antigen, monoclonal


CEA-B18, CEA-D14, CEA-GOLD 1, T84.6, CEA-GOLD 2, CEA 11, CEA-GOLD 3, CEA 27, CEA-GOLD 4, CEA 41, CEA-GOLD 5, T84.1, CEA-M, A5B7, CEJ065, IL-7, T84.66, TF3H8-1, 0062, D14, alpha-7, PARLAM 1, ZC23, CEM010, A115, COL-1, AF4, 12.140.10, 11-7, M773, CEA-M431_31, CEJO65, mCEA


Adenoid Cystic Carcinoma; Hidradenocarcinoma; Porocarcinoma; Sebaceous Carcinoma; Squamoid “Eccrine” Ductal Carcinoma


Chromogranin-A


pituitary secretory protein 1


PHE-5, PHE5, E001, DAK-A3


Dermal Nerve Sheath Myxoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sinonasal Melanoma


Chymase


serine protease found in mast cells and basophils; acts as a mediator of inflammation



Cutaneous and Systemic Mastocytosis


Chymotrypsin


digestive enzyme synthesized in pancreas, involved in proteolysis



Dermatofibrosarcoma Protuberans


CK-HMW-NOS


cytokeratin high molecular weight, not otherwise specified


CK-HMW, HMWCK, 34bE12, CK903


Atypical Fibroxanthoma; Porocarcinoma; Poroma and Dermal Duct Tumor; Squamous Cell Carcinoma (and Variants)


CK-PAN


cytokeratin-pan (AE1/AE3/LP34); cocktail of high and low molecular weight cytokeratins


keratin pan, MAK-6, K576, LU-5, KL-1, KC-8, MNF 116, pankeratin, pancytokeratin


Angiosarcoma; Atypical Fibroxanthoma; Basal Cell Carcinoma; Cutaneous Rhabdomyosarcoma; Epithelioid Hemangioendothelioma; Epithelioid Sarcoma; Glomus Tumors; Granular Cell Tumor; Leiomyosarcoma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Malignant Mixed Tumor; Myofibroma and Myofibromatosis; Neuromas; Oral Melanoma; PEComas; Perineurioma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sinonasal Melanoma; Squamomelanocytic Tumor; Squamous Cell Carcinoma (and Variants)


CK5/6


cytokeratin 5/6, high molecular weight cytokeratins


D5/16 B4


Atypical Fibroxanthoma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Sarcoma; Extramammary Paget Disease; Leiomyosarcoma; Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Malignant Mixed Tumor; Porocarcinoma; Poroma and Dermal Duct Tumor; Primary Cutaneous Mucinous Carcinoma; Sebaceous Carcinoma; Spiradenoma; Squamoid “Eccrine” Ductal Carcinoma; Squamous Cell Carcinoma (and Variants); Squamous Cell Carcinoma In Situ (Bowen Disease); Syringocystadenoma Papilliferum


CK7


cytokeratin 7, low molecular weight cytokeratin


K72.7, KS7.18, OVTL 12/30, LDS-68, CK 07


Clear Cell Papulosis; Cutaneous Ciliated Cyst; Cylindroma; Epithelioid Sarcoma; Extramammary Paget Disease; Histiocytic Sarcoma; Median Raphe Cyst; Melanoma In Situ, Superficial Spreading Type; Metastatic Tumors to the Skin; Microcystic Adnexal Carcinoma; Mucosal Melanoma (Genital); Primary Cutaneous Mucinous Carcinoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sebaceous Carcinoma; Squamoid “Eccrine” Ductal Carcinoma; Squamous Cell Carcinoma In Situ (Bowen Disease); Toker Cell Hyperplasia; Tricholemmal Carcinoma


CK8/18/CAM5.2


cytokeratin 8/18; simple epithelialtype cytokeratins


5D3, Zym5.2, CAM 5.2, KER 10.11, NCL-5D3, cytokeratin LMW


Angiomatoid Fibrous Histiocytoma; Epithelioid Sarcoma; Primary Neuroendocrine (Merkel Cell) Carcinoma


CK10


cytokeratin 10


LHP1, DE-K10, RKSE60


Vellus Hair Cyst


CK13


cytokeratin 13


KS13.1, KS-1A3, AE8, 2D7


Median Raphe Cyst


CK17


cytokeratin 17


E3


Squamoid “Eccrine” Ductal Carcinoma; Vellus Hair Cyst


CK19


cytokeratin 19, low molecular weight cytokeratin


BA17, RCK108, LP2K, B170, A53-BA2, KS19.1, 170.2.14


Cylindroma; Epithelioid Sarcoma


CK20


cytokeratin 20, low molecular weight cytokeratin


KS20.8


Basal Cell Carcinoma; Cutaneous Ciliated Cyst; Cutaneous Rhabdomyosarcoma; Dermatofibroma and Fibrous Histiocytoma; Epithelioid Sarcoma; Extramammary Paget Disease; Leukemia Cutis; Median Raphe Cyst; Metastatic Skin Tumors; Metastatic Tumors to the Skin; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Primary Cutaneous Mucinous Carcinoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sebaceous Carcinoma; Spiradenoma; Squamous Cell Carcinoma In Situ (Bowen Disease); Toker Cell Hyperplasia; Trichoblastoma; Trichoepithelioma


CK903


cytokeratin-HMW, not otherwise specified


CK-HMW, CK-HMW-NOS, HMWCK, 34bE12


Atypical Fibroxanthoma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Leiomyosarcoma; Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Squamous Cell Carcinoma (and Variants)


CLA


cutaneous lymphocyte antigen



Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia Cutis; Systemic T-cell and NK-cell Lymphomas Involving the Skin


Claudin-1


senescence-associated epithelial membrane protein


JAD.8


Ectopic Meningioma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Perineurioma


Clusterin


clusterin, alpha chain specific


41D, E5


Angioimmunoblastic T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


Collagen II


major component of articular and hyaline cartilage


2B1.5


Cutaneous Mixed Tumor (Chondroid Syringoma)


Collagen IV


major constituent of the basement membranes along with laminins, proteoglycans, and enactins


CIV22, COL4A [1-5], collagen α-1(IV) chain


Cutaneous Mixed Tumor (Chondroid Syringoma); Glomus Tumors; Granular Cell Tumor; Perineurioma; Schwannoma (Neurilemmoma)


Cutaneous lymphocyte antigen


skin homing receptor


CLA


Leukemia Cutis; Primary Cutaneous Anaplastic Large Cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CXCL13


chemokine CXC ligand 13, B lymphocyte chemoattractant


BCA-1, BLC, BLR1L, ANGIE, CXC chemokine BCL, SCYB13


Adult T-cell Leukemia/Lymphoma; Angioimmunoblastic T-cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


CXCR3


chemokine CXC receptor R3


1C6


Intravascular large B-cell Lymphoma


Cyclin-D1


protein with important cell cycle regulatory functions


bcl-1 (cyclin D1) A-12, PRAD1, AM29, DCS-6, SP4, 5D4, D1GM, P2D11F11, CCND1Cyl-1


Chondroid Lipoma; Epithelioid Sarcoma; Primary Dermal Melanoma; Systemic B-cell Lymphomas Involving the Skin


Cytokeratin




Atypical Fibroxanthoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Childhood Melanoma; Chondroid Lipoma; Clear Cell Papulosis; Cutaneous Marginal Zone B-cell Lymphoma; Cutaneous Mixed Tumor (Chondroid Syringoma); Cutaneous Rhabdomyosarcoma; Epithelioid Hemangioendothelioma; Epithelioid Sarcoma; Extramammary Paget Disease; Fibromatosis; Glomus Tumors; Hidradenocarcinoma; Histiocytic Sarcoma; Metastatic Skin Tumors; Metastatic Tumors to the Skin; Oral Melanoma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Pilomatrixoma and Pilomatrical Carcinoma; Plexiform Fibrohistiocytic Tumor; Polyvinylpyrrolidone Storage Disease; Porocarcinoma; Sebaceous Adenoma; Squamomelanocytic Tumor; Syringofibroadenoma; Trichoblastoma; Vellus Hair Cyst


Cytokeratin 5/6


high molecular weight cytokeratins


D5/16 B4


Hidradenocarcinoma; Metastatic Tumors to the Skin


Cytokeratin 7


low molecular weight cytokeratin


K72.7, KS7.18, OVTL 12/30, LDS-68, CK 07


Metastatic Tumors to the Skin; Sebaceous Adenoma


Cytokeratin 20


low molecular weight cytokeratin


KS20.8


Metastatic Tumors to the Skin; Pilomatrixoma and Pilomatrical Carcinoma; Trichoblastoma


D2-40


reacts with an O-linked sialoglycoprotein found on lymphatic endothelium


podoplanin, M2A


Lymphangioma and Superficial Lymphangioma; Metastatic Tumors to the Skin; Papillary Intralymphatic Angioendothelioma (Dabska Tumor); Primary Dermal Melanoma; Progressive Lymphangioma; Retiform Hemangioendothelioma; Rosai-Dorfman Disease; Sebaceous Carcinoma; Squamous Cell Carcinoma (and Variants)


Desmin


class III intermediate filaments found in muscle cells


M760, DE-R-11, D33, DE5, DE-U-10, ZC18


Acral Fibrokeratoma; Angioleiomyoma; Angiomatoid Fibrous Histiocytoma; Angiomyofibroblastoma; Angiosarcoma; Atypical Fibroxanthoma; Childhood Melanoma; Collagenous Fibroma; Congenital Smooth Muscle Hamartoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Cutaneous Rhabdomyosarcoma; Dermal Nerve Sheath Myxoma; Dermatofibrosarcoma Protuberans; Dermatomyofibroma; Digital Fibromatosis (Infantile Digital Fibromatosis); Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Sarcoma; Fibromatosis; Fibrous Hamartoma of Infancy; Giant Cell Tumor of Tendon Sheath; Glomus Tumors; Granular Cell Tumor; Hibernoma; Leiomyoma (Pilar); Leiomyosarcoma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Myofibroma and Myofibromatosis; Oral Melanoma; Papillary Endothelial Hyperplasia (Masson Tumor); Paraganglioma-like Dermal Melanocytic Tumor; PEComas; Perineurioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Plexiform Fibrohistiocytic Tumor; Pseudosarcomatous Fibroblastic Proliferations; Reticulohistiocytoma; Rhabdomyoma; Schwannoma (Neurilemmoma); Sinonasal Melanoma; Squamous Cell Carcinoma (and Variants); Superficial Malignant Peripheral Nerve Sheath Tumor


E-cadherin


epithelial calcium dependent adhesion molecule


36B5, ECH-6, ECCD-2, CDH1, 5H9, NCH 38, Clone 36, 4A2 C7, E9, 67A4, HECD-1, SC-8426


Granular Cell Tumor


E2A



Anti-TCF3, TCF3, immunoglobulin enhancerbinding factor E12/E47


Primary Cutaneous Follicle Center Lymphoma


EBER


Epstein-Barr virus encoded RNA



Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Plasmacytoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Histiocytic Sarcoma; Leiomyosarcoma; Lymphomatoid Granulomatosis; Systemic T-cell and NK-cell Lymphomas Involving the Skin


EGFR


v-erb b1 erythroblastic leukemia viral gene, epidermal growth factor receptor


2-18C9, EGFR1, EGFR PHRMDX, NCL-R1, H11, C-ERBB-1, E30, EGFR.113, 31G73C6, 2-18C9


Myxoinflammatory Fibroblastic Sarcoma


EMA


epithelial membrane antigen


GP1.4, 214D4, MC5, E29, LICRLON- M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8, MUC1, MAM6, CA15.3, MUC01


Acral Fibrokeratoma; Adenoid Cystic Carcinoma; Angiosarcoma; Apocrine Tubular Adenoma; Atypical Fibroxanthoma; Basal Cell Carcinoma; Cellular Neurothekeoma; Chondroid Lipoma; Cutaneous Ciliated Cyst; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Cutaneous Mixed Tumor (Chondroid Syringoma); Cutaneous Myxoma and Angiomyxoma; Cutaneous Rhabdomyosarcoma; Cylindroma; Dermal Nerve Sheath Myxoma; Digital Fibromatosis (Infantile Digital Fibromatosis); Eccrine Carcinoma; Eccrine Hamartomas; Ectopic Meningioma; Epithelioid Hemangioendothelioma; Epithelioid Sarcoma; Fibromatosis; Granular Cell Tumor; Hidradenocarcinoma; Hidradenoma; Histiocytic Sarcoma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Lymphoepitheliomalike Carcinoma of the Skin (LELCS); Melanoma In Situ, Superficial Spreading Type; Microcystic Adnexal Carcinoma; Myxoinflammatory Fibroblastic Sarcoma; Nasal Glial Heterotopia; Neurofibroma; Neuromas; Papillary Eccrine Adenoma; Perineurioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Porocarcinoma; Primary Cutaneous Anaplastic Large Cell Lymphoma; Sebaceoma (Sebaceous Epithelioma); Sebaceous Carcinoma; Sinonasal Melanoma; Spiradenoma; Squamoid “Eccrine” Ductal Carcinoma; Squamous Cell Carcinoma (and Variants); Squamous Cell Carcinoma In Situ (Bowen Disease); Superficial Acral Fibromyxoma; Syringocystadenoma Papilliferum; Syringoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin; Toker Cell Hyperplasia; Trichoblastoma; Tricholemmal Carcinoma


EMA/MUC1


epithelial membrane antigen


EMA, GP1.4, 214D4, MC5, E29, LICRLON-M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8, MUC1, MAM6, CA15.3, MUC01


Angiomatoid Fibrous Histiocytoma; Congenital Smooth Muscle Hamartoma; Epithelioid Sarcoma; Extramammary Paget Disease; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Myxofibrosarcoma; Neurofibroma; Perineurioma; Superficial Acral Fibromyxoma


EpCam/BER-EP4/CD326


epithelial cell adhesion molecule


AUA1, VU-1D9, EPCAM, C10, HEA125, BEREP4


Basal Cell Carcinoma; Primary Neuroendocrine (Merkel Cell) Carcinoma


Epithelial membrane antigen



EMA, GP1.4, 214D4, MC5, E29, LICRLON-M8, BC3, DF3, VU3D1, MUSEII, RD-1, MA695, MA552, PS2P446, 115D8, MUC1, MAM6, CA15.3, MUC01


Clear Cell Papulosis; Cutaneous Mixed Tumor (Chondroid Syringoma); Ectopic Meningioma; Fibrolipomatous Hamartoma of Nerve; Oral Melanoma; Papillary Eccrine Adenoma


ER


estrogen receptor protein


1D5, 6F11, SP1, 15D, H222, TE111, ERP, ER1D5, NCLER611, NCL-ER-LH2, PGP-1A6


Angiomyofibroblastoma; Apocrine Carcinoma (Apocrine Adenocarcinoma); Metastatic Tumors to the Skin; Primary Cutaneous Mucinous Carcinoma


ERP


estrogen receptor protein


1D5, 6F11, SP1, 15D, H222, TE111, ER, ER1D5, NCLER611, NCL-ER-LH2, PGP-1A6


Leiomyosarcoma; Primary Cutaneous Mucinous Carcinoma


Factor XIIIa


fibrin stabilizing factor


FXIIIA


Angiofibroma and Related Lesions; Juvenile and Adult-type Xanthogranuloma; Leiomyosarcoma; Non-Langerhans Cell Histiocytoses


FAS


fatty acid synthase


CD95/fas


Cutaneous Marginal Zone B-cell Lymphoma; Extranodal NK/T-cell Lymphoma, Nasal Type


Fascin


marker for Reed-Sternberg cells of Hodgkin disease


55K2


Non-Langerhans Cell Histiocytoses


Fibronectin


extracellular matrix glycoprotein


FN1, A0245, CIG


Cutaneous Mixed Tumor (Chondroid Syringoma)


FLI-1


Friend leukemia virus integration 1


EWSR2, GI146-222, SC356, FLK-1, FLT-1


Angiosarcoma; Epithelioid Hemangioendothelioma; Epithelioid Sarcoma; Kaposi Sarcoma; Kaposiform Hemangioendothelioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


FOXP1


forkhead box transcription factor P1


JC12


Diffuse Large B-cell Lymphoma, Leg Type


FOXP3


forkhead box transcription factor P3


FoxP3


Adult T-cell Leukemia/Lymphoma


FVIIIRAg


factor VIII-related antigen


FVIIIRAG, F8/86, von Willebrand factor


Angiolymphoid Hyperplasia with Eosinophilia; Epithelioid Sarcoma; Extramedullary Hematopoiesis; Infantile Hemangioma; Lymphangioma and Superficial Lymphangioma; Papillary Intralymphatic Angioendothelioma (Dabska Tumor); Retiform Hemangioendothelioma; Spindle Cell Hemangioma


FXIIIA


factor XIIIA (fibrin stabilizing factor)


factor XIIIa


Acral Fibrokeratoma; Dermatofibroma and Fibrous Histiocytoma; Dermatofibrosarcoma Protuberans; Dermatomyofibroma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Histiocytoma; Juvenile and Adult-type Xanthogranuloma; Multinucleate Cell Angiohistiocytoma; Non-Langerhans Cell Histiocytoses; Pleomorphic Fibroma; Plexiform Fibrohistiocytic Tumor; Reticulohistiocytoma; Sclerotic Fibroma


GCDFP-15


gross cystic fluid protein 15


SABP, GPIP4, Gp17, 23A3, BRST-2, D6 (GROSS CYSTIC DISEASE FLUID PROTEIN)


Apocrine Carcinoma (Apocrine Adenocarcinoma); Apocrine Tubular Adenoma; Clear Cell Papulosis; Cutaneous Ciliated Cyst; Extramammary Paget Disease; Metastatic Tumors to the Skin; Primary Cutaneous Mucinous Carcinoma; Sebaceous Carcinoma; Syringocystadenoma Papilliferum; Toker Cell Hyperplasia


GFAP


glial fibrillary acidic protein


6F2, M761, GA-51, GFP-8A


Dermal Nerve Sheath Myxoma; Granular Cell Tumor; Nasal Glial Heterotopia; Neurofibroma; Neuromas; Perineurioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Schwannoma (Neurilemmoma); Sinonasal Melanoma


Glucose transporter 1



GLUT1


Branchial Cleft Cyst


GLUT1


glucose transporter 1



Infantile Hemangioma; Kaposiform Hemangioendothelioma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Perineurioma


GLUT1-cytoplasm


glucose transporter 1-cytoplasmic


GLUT1-CYT


Perineurioma


Glycophorin A


sialoglycoprotein of the human erythrocyte membrane


CD235a, JC159, GYPA, CD235a


Extramedullary Hematopoiesis


Granzyme B


neutral serine protease


GZM-B, 11F1, GR-B7


Subcutaneous Panniculitis-like T-cell Lymphoma


Gross cystic fluid protein 15



GCDPF-15, SABP, GPIP4, Gp17, 23A3, BRST-2, D6 (GROSS CYSTIC DISEASE FLUID PROTEIN)


Clear Cell Papulosis


GZM-B


neutral serine protease


Granzyme B, 11F1, GR-B7


Extranodal NK/T-cell Lymphoma, Nasal Type; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma


GZM-M


Serine protease contained by NK cells and some activated lymphocytes



Subcutaneous Panniculitis-like T-cell Lymphoma


H-caldesmon


High molecular weight caldesmon


H-CD


Angiomatoid Fibrous Histiocytoma; Childhood Melanoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Cutaneous Rhabdomyosarcoma; Fibromatosis; Glomus Tumors; Granular Cell Tumor; Leiomyoma (Pilar); Plexiform Fibrohistiocytic Tumor;


HCAD


H-caldesmon (high molecular weight caldesmon)


H-CD


Angioleiomyoma; Angiomatoid Fibrous Histiocytoma; Congenital Smooth Muscle Hamartoma; Glomus Tumors; PEComas


Hep-Par1


hepatocyte paraffin 1


OCH1E5.2.10, HEPPAR1


PEComas


HER2


v-erb-b2 erythroblastic leukemia viral gene protein, human epidermal growth factor receptor 2


c-erb-B2, HER2/neu, NEU, HER-2, NCL-CBE1, 10A7, 9G6.10, SP3, 4B5, P185, 9G6.20, A0485, C-ERBB-2, CB11, ERBB-2, 3B5, TAB250, HERCEPTEST, E2-4001, HER-2_NEU


Toker Cell Hyperplasia


HGAL


human germinal center-associated lymphoma



Primary Cutaneous Follicle Center Lymphoma


hHa1


stains specifically human hair keratin expressed starting from the upper part of the hair matrix, lower cortex, and hair cuticle



Pilomatrixoma and Pilomatrical Carcinoma


HHV8


human herpes virus 8


Kaposi sarcoma-associated herpes virus, KSHV, HUMAN HERPESVIRUS-8 LATENT NUCLEAR ANTIGEN-1, 13B10, LNA-1


Angiolipoma; Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Capillary, Venous, and Cavernous Hemangiomas; Dermatofibroma and Fibrous Histiocytoma; Kaposi Sarcoma; Kaposiform Hemangioendothelioma; Multinucleate Cell Angiohistiocytoma; Progressive Lymphangioma; Pseudosarcomatous Fibroblastic Proliferations; Retiform Hemangioendothelioma; Spindle Cell Hemangioma; Venous Lake


HLA-DR


human leukocyte antigen DR


DK22, LN3, TAL.1B5, LK8D3


Blastic Plasmacytoid Dendritic Cell Neoplasm


HMB-45


antigen present in melanocytic tumors such as melanomas


LB39 AA, CMM1, CMM, DNS, FAMMM, Mart1, Melan-A, MLM, tyrosinase


Actinic Keratosis; Angiofibroma and Related Lesions; Angioleiomyoma; Angiolipoma; Atypical Fibroxanthoma; Atypical/Borderline and Malignant Spitz Tumors; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cellular Blue Nevi; Cellular Neurothekeoma; Childhood Melanoma; Conventional Blue Nevi; Dermal Nerve Sheath Myxoma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Histiocytoma; Epithelioid Sarcoma; Extramammary Paget Disease; Fibromatosis; Halo Nevi; Histiocytic Sarcoma; Leiomyosarcoma; Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Melanoma In Situ, NOS; Melanoma, Lentigo Maligna Type; Metastatic Skin Tumors; Neurofibroma; Neuromas; Oral Melanoma; Paragangliomalike Dermal Melanocytic Tumor; PEComas; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Pigmented Spindle Cell Nevus (Reed Nevus); Primary Dermal Melanoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Reticulohistiocytoma; Rhabdomyoma; Schwannoma (Neurilemmoma); Sinonasal Melanoma; Squamous Cell Carcinoma (and Variants); Superficial Malignant Peripheral Nerve Sheath Tumor; Other Unusual and Rare Variants of Melanoma


HPV


human papillomavirus



HPV-related Epidermal Cyst


HTLV-1


p40 tax antibody


Human T-cell Lymphotropic Virus, Human T-lymphotropic virus Type 1 (HTLV-I), Adult T-cell lymphoma virus type 1


Adult T-cell Leukemia/Lymphoma; Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Leukemia Cutis


Human germinal center-associated lymphoma



HGAL


Primary Cutaneous Follicle Center Lymphoma


IgA


immunoglobulin A


IGA


Primary Cutaneous Follicle Center Lymphoma


IgD


immunoglobulin D


IGD


Diffuse Large B-cell Lymphoma, Leg Type; Primary Cutaneous Follicle Center Lymphoma


IgF-2


insulin growth factor-like 2


W2-H1


Infantile Hemangioma


IgG


immunoglobulin G


IGG


Acantholytic and Acantholytic Dyskeratotic Acanthoma; Primary Cutaneous Follicle Center Lymphoma; Prurigo Nodularis; Pseudoepitheliomatous Hyperplasia


IgM


immunoglobulin M


IGM


Diffuse Large B-cell Lymphoma, Leg Type; Primary Cutaneous Follicle Center Lymphoma


IL-15


interleukin 15



Keloid and Cellular Scar


Immunoglobulin A



IgA, IGA


Subcutaneous Panniculitis-like T-cell Lymphoma


Inhibin-α


produced by ovarian granulosa cells; inhibits production or secretion of pituitary gonadotropins, a sensitive marker for majority of sex cord/stromal tumors



Granular Cell Tumor


INI1


member of SWI/SNF chromatin remodeling complex


BAF47/SNF5, SNF5


Angiosarcoma; Epithelioid Sarcoma; Fibromatosis; Myxoinflammatory Fibroblastic Sarcoma


IRF-4


interferon regulatory factor 4


MUM1P, clone MUM1, MUM1-IRF.4, MUM1, M17


Primary Cutaneous Follicle Center Lymphoma


Kappa


kappa light chain


KAPPA, κ light chain


Primary Cutaneous Follicle Center Lymphoma; Systemic B-cell Lymphomas Involving the Skin


KBA62


Anti-melanoma associated antigen


KBA6.2


Childhood Melanoma; Desmoplastic Melanoma


Ki-67


Ki-67 (MIB-1); marker of cell proliferation


MMI, KI88, IVAK-2, MIB1


Actinic Cheilitis; Atypical Vascular Lesion; Atypical/Borderline and Malignant Spitz Tumors; Basal Cell Carcinoma; Diffuse Large B-cell Lymphoma, Leg Type; Extranodal NK/T-cell Lymphoma, Nasal Type; Granular Cell Tumor; Halo Nevi; Hidradenocarcinoma; Hidrocystoma (Apocrine and Eccrine); Intravascular Large B-cell Lymphoma; Kaposi Sarcoma; Large Cell Acanthoma; Lymphomatoid Papulosis; Malignant Cellular Blue Nevus (Melanoma Arising in Cellular Blue Nevus); Melanoma In Situ, NOS; Melanoma In Situ, Superficial Spreading Type; Metastatic Skin Tumors; Microcystic Adnexal Carcinoma; Mycosis Fungoides (and Subtypes); Myxoinflammatory Fibroblastic Sarcoma; Nevoid Melanoma; Non-Langerhans Cell Histiocytoses; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Pigmented Spindle Cell Nevus (Reed Nevus); Poroma and Dermal Duct Tumor; Primary Dermal Melanoma; Sclerotic Fibroma; Sebaceoma (Sebaceous Epithelioma); Sebaceous Carcinoma; Systemic B-cell Lymphomas Involving the Skin; Trichoblastoma; Trichoepithelioma


Lambda


lambda light chain


λ light chain, LAMBDA


Primary Cutaneous Follicle Center Lymphoma; Systemic B-cell Lymphomas Involving the Skin


Laminin


major protein in basal lamina


LAMININ-4C7, 4C12.8, LAM-89


Cutaneous Mixed Tumor (Chondroid Syringoma)


Langerin


CD207 molecule


CD207


Histiocytic Sarcoma; Non-Langerhans Cell Histiocytoses


LCA


leukocyte common antigen


PD7/26, 1.22/4.14, T29/33, CD45RB, RP2/18, CD45, PD7, 2D1, 2B11+PD7/26


Extramammary Paget Disease; Large Cell Acanthoma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


LEP


leptin



Lipoma


LEU-7


β-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


CD57, NK1, HNK-1, TB01, B3GAT1


Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


LMP1


Epstein-Barr virus latent membrane protein


EBV-LMP, CS 1-4


Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Systemic B-cell Lymphomas Involving the Skin


Lysozyme


1,4-beta N-acetylmuramidase C


Lyz, Lzm, Ec3.2.1.17


Dermatofibrosarcoma Protuberans; Histiocytic Sarcoma; Leukemia Cutis; Multicentric Reticulohistiocytosis; Multinucleate Cell Angiohistiocytoma; Plexiform Fibrohistiocytic Tumor; Reticulohistiocytoma


LYVE-1


lymph vessel endothelial hyaluronan receptor 1



Lymphangioma and Superficial Lymphangioma


MAC387


macrophage antibody



Multicentric Reticulohistiocytosis


Mammaglobin


Breast tissue-specific glycoprotein


304-1A5


Apocrine Carcinoma (Apocrine Adenocarcinoma); Metastatic Tumors to the Skin


Mart-1


mart-1 clone of Melan-A



Mucosal Melanoma (Genital); PEComas


MDM2


murine double minute oncogene (mdm2)


HDM2, IF2, 2A10, 1B10, SMP14, murine double minute 2


Atypical Lipomatous Tumor and Liposarcoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Hibernoma; PEComas; Spindle Cell and Pleomorphic Lipoma


Melan-A


melanoma antigen recognized by T cells 1 (MART-1); protein found on melanocytes; melanocyte differentiation antigen


M2-7C10, CK-MM


Angiofibroma and Related Lesions; Atypical/Borderline and Malignant Spitz Tumors; Desmoplastic Melanoma; Fibromatosis; Halo Nevi; Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Metastatic Skin Tumors; Sinonasal Melanoma; Squamomelanocytic Tumor


Melan-A103


clone of Melan-A


A103


Angioleiomyoma; Atypical Fibroxanthoma; Atypical/Borderline and Malignant Spitz Tumors; Cellular Neurothekeoma; Desmoplastic Melanoma; Halo Nevi; Metastatic Skin Tumors; Oral Melanoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sinonasal Melanoma; Squamomelanocytic Tumor


met


met proto-oncogene


8F11, C-28, C-MET


Cutaneous and Systemic Mastocytosis; Metastatic Tumors to the Skin


MIC2


cell surface glycoprotein for migration, T-cell adhesion


CD99, CD99-MEMB, MIC2, 12E7, HBA71, O13, P30/32MIC2, M3601


Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


Micropthalmia transcription factor



MITF, 34CA5, D5, C5+D5


Sinonasal Melanoma


MITF


micropthalmia transcription factor


34CA5, D5, C5+D5


Atypical Fibroxanthoma; Cellular Neurothekeoma; Childhood Melanoma; Metastatic Skin Tumors; Oral Melanoma; PEComas; Plexiform Fibrohistiocytic Tumor; Sinonasal Melanoma; Other Unusual and Rare Variants of Melanoma


MLH1


mutL homolog 1


HMLH1, G168-15, G168-728, MMR family; HNPCC2, COCA2


Sebaceoma (Sebaceous Epithelioma); Sebaceous Adenoma; Sebaceous Carcinoma


MPO


myeloperoxidase



Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous and Systemic Mastocytosis; Extramedullary Hematopoiesis; Histiocytic Sarcoma; Leukemia Cutis


MSA


actin, smooth muscle


actin-sm, ASM-1, CGA7, 1A4, HUC1-1


Adenoid Cystic Carcinoma; Atypical Fibroxanthoma; Childhood Melanoma; Dermatomyofibroma; Leiomyosarcoma; Sinonasal Melanoma


MSH2


mutS homolog 2


FE11


Sebaceoma (Sebaceous Epithelioma); Sebaceous Adenoma; Sebaceous Carcinoma


MSH6


mutS homolog 6


clone 44, GRBP.P1, DNA mismatch repair protein MSH6 antibody, G/T mismatch binding protein antibody, GTBP antibody, GTMBP antibody, HNPCC 5 antibody, HNPCC5 antibody, HSAP antibody, MSH 6 antibody, mutS (E. coli) homolog 6 antibody


Sebaceoma (Sebaceous Epithelioma); Sebaceous Carcinoma


MUC4


mucin 4, tracheobronchial


8G7


Low-Grade Fibromyxoid Sarcoma (Evans Tumor)


MUM1


Interferon regulatory factor 4


IRF-4, MUM1P, clone MUM1, MUM1-IRF.4, M17


Blastic Plasmacytoid Dendritic Cell Neoplasm; Diffuse Large B-cell Lymphoma, Leg Type; Leukemia Cutis; Lymphomatoid Papulosis; Primary Cutaneous Follicle Center Lymphoma; Systemic B-cell Lymphomas Involving the Skin


MxA


Protein induced by alpha interferon protein



Blastic Plasmacytoid Dendritic Cell Neoplasm


myc


myelocytomatosis viral oncogene


C-MYC, c-myc, 9E10, 9E11, 1-262


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Marginal Zone B-cell Lymphoma; Diffuse Large B-cell Lymphoma, Leg Type


Myeloperoxidase



MPO


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous and Systemic Mastocytosis; Extramedullary Hematopoiesis; Histiocytic Sarcoma


MYOD1


myogenic differentiation 1


5.8A, 5.2F


Angiomatoid Fibrous Histiocytoma; Congenital Smooth Muscle Hamartoma; Cutaneous Rhabdomyosarcoma; Epithelioid Sarcoma; Pseudosarcomatous Fibroblastic Proliferations; Rhabdomyoma; Sinonasal Melanoma


Myogenin


myogenin


F5D, MYF3, MYF4, MYOGENIN, LO26


Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Congenital Smooth Muscle Hamartoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Cutaneous Rhabdomyosarcoma; Epithelioid Sarcoma; Granular Cell Tumor; Hibernoma; Pseudosarcomatous Fibroblastic Proliferations; Rhabdomyoma; Sinonasal Melanoma; Superficial Malignant Peripheral Nerve Sheath Tumor


Myoglobin


iron and oxygen-building protein found in muscle tissue


MG-1


Botryoid Rhabdomyosarcoma; Gingival Granular Cell Tumor of the Newborn; Inflammatory Myofibroblastic Tumor; Rhabdomyoma; Rhabdomyosarcoma


Neurofilament protein


neurofilament H/M phosphorylated protein


NFP, TPNFP-1A3, SMI31, SMI33, NFP, SMI32, TA-51, 2F11


Neurofibroma; Neuromas; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


NFP


neurofilament H/M phosphorylated protein


TPNFP-1A3, SMI31, SMI33, NFP, SMI32, TA-51, 2F11


Neurofibroma; Neuromas; Perineurioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor


NGFR


nerve growth factor receptor



Granular Cell Tumor


NKI/C3


tetraspan intracellular granule protein


CD63, basophil activation test in allergy


Cellular Neurothekeoma Plexiform Fibrohistiocytic Tumor


NSE


neuron specific enolase


BSS/H14


Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Mixed Tumor (Chondroid Syringoma); Granular Cell Tumor; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sinonasal Melanoma


Nuclear p53


p53 tumor suppressor gene protein


D07, 21N, BP53-12-1, AB6, CM1, PAB1801, DO1, BP53-11, PAP240, RSP53, MU195, P53


Sebaceoma (Sebaceous Epithelioma); Sebaceous Carcinoma


OCT2


octamer binding transcription factor 2


SC233


Lymphomatoid Granulomatosis


p15


cyclin-dependent kinase 4 inhibitor B


P15-INK4B


Primary Cutaneous Follicle Center Lymphoma


p16


cyclin-dependent kinase 4 inhibitor 2A


P16_INK4A, E6H4, sc1661, JC8, JZ11, P16, G175-405, F-12, DCS-50, 6H12, 16P07, 16P04


Atypical/Borderline and Malignant Spitz Tumors; Childhood Melanoma; Condyloma Acuminatum (Genital Wart); Malignant Cellular Blue Nevus (Melanoma Arising in Cellular Blue Nevus); Melanoma In Situ, NOS; Melanoma In Situ, Superficial Spreading Type; Penile and Vulvar Intraepithelial Neoplasia; Pigmented Spindle Cell Nevus (Reed Nevus); Primary Cutaneous Follicle Center Lymphoma; Sinonasal Melanoma; Syringocystadenoma Papilliferum


p53


p53 tumor suppressor gene protein



Actinic Keratosis; Atypical Vascular Lesion; Basal Cell Carcinoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Granular Cell Tumor; Hidradenocarcinoma; Microcystic Adnexal Carcinoma; Penile and Vulvar Intraepithelial Neoplasia; Primary Dermal Melanoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sebaceoma (Sebaceous Epithelioma); Sebaceous Carcinoma; Superficial Malignant Peripheral Nerve Sheath Tumor; Trichoblastoma; Trichoepithelioma


p63


tumor protein p63


H-137, 7JUL


Adenoid Cystic Carcinoma; Atypical Fibroxanthoma; Basal Cell Carcinoma; Childhood Melanoma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Sarcoma; Extramammary Paget Disease; Hidradenocarcinoma; Histiocytic Sarcoma; Leiomyosarcoma; Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Malignant Mixed Tumor; Median Raphe Cyst; Metastatic Skin Tumors; Metastatic Tumors to the Skin; Papillary Eccrine Adenoma; Porocarcinoma; Primary Cutaneous Mucinous Carcinoma; Proliferating Pilar (Trichilemmal) Cyst/Tumor; Sebaceous Carcinoma; Squamoid “Eccrine” Ductal Carcinoma; Squamous Cell Carcinoma (and Variants); Syringocystadenoma Papilliferum


pax-5


paired box gene 2


Z-RX2, PAX-2


Angioimmunoblastic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Plasmacytoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Histiocytic Sarcoma; Intravascular Large B-cell Lymphoma; Leukemia Cutis; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous Follicle Center Lymphoma; Systemic B-cell Lymphomas Involving the Skin; Systemic T-cell and NK-cell Lymphomas Involving the Skin


pax-8


paired box gene 8



Sebaceous Carcinoma


PCNA


proliferating cell nuclear antigen


19 A2, PC10


Large Cell Acanthoma; Malignant Cellular Blue Nevus (Melanoma Arising in Cellular Blue Nevus)


PD-1


programmed cell death protein 1


EH12, NAT105, programmed death 1


Angioimmunoblastic T-cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma


Perforin



P1-8, PE-41-PU, 5B10


Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Lymphomatoid Papulosis; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma


PGP9.5


protein gene product 9.5


31A3,13C4


Granular Cell Tumor; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Plexiform Fibrohistiocytic Tumor


Podoplanin


transmembrane mucoprotein (38 kd) recognized by the D2-40 monoclonal antibody


D2-40, M2A


Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Atypical Vascular Lesion; Cellular Neurothekeoma; Epithelioid Hemangioendothelioma; Kaposi Sarcoma; Kaposiform Hemangioendothelioma; Lymphangioma and Superficial Lymphangioma; Metastatic Tumors to the Skin; Progressive Lymphangioma; Rosai-Dorfman Disease; Sebaceoma (Sebaceous Epithelioma); Sebaceous Carcinoma


PR


progesterone receptor protein


PRP, 10A9, PGR-1A6, KD68, PGR-ICA, PRP-P, PRI, 1A6, 1AR, HPRA3, PGR-636, 636, PR88, NCL-PGR


Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angiomyofibroblastoma; Apocrine Carcinoma (Apocrine Adenocarcinoma); Cutaneous Gamma-Delta T-cell Lymphoma; Metastatic Tumors to the Skin; Primary Cutaneous Mucinous Carcinoma


PRAD1


protein with important cell cycle regulatory functions


Cyclin-D1, bcl-1 (cyclin D1) A-12, AM29, DCS-6, SP4, 5D4, D1GM, P2D11F11, CCND1Cyl-1


Systemic B-cell Lymphomas Involving the Skin


Prostate specific antigen



PSA, PSA-M, PSA, ER-PR8, PSA-P, F5


Metastatic Tumors to the Skin


PROX1


critical regulator of lymphangiogenesis



Lymphangioma and Superficial Lymphangioma


PSA


prostate specific antigen


PSA-M, PSA, ER-PR8, PSA-P, F5


Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Metastatic Tumors to the Skin; Pilar Sheath Acanthoma


PTEN


phosphatase and tensin homolog


PN37


Fibrolipomatous Hamartoma of Nerve; Mycosis Fungoides (and Subtypes); Tricholemmoma


RCC


renal cell carcinoma antibody


66.4C2, PN-15, RCC MA


Hidradenoma; Metastatic Tumors to the Skin; Sebaceous Carcinoma


S100


low molecular weight protein normally present in cells derived from neural crest (Schwann cells, melanocytes, and glial cells), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes


S-100, A6, 15E2E2, Z311, 4C4.9


Actinic Keratosis; Adenoid Cystic Carcinoma; Angiofibroma and Related Lesions; Angioleiomyoma; Angiomyofibroblastoma; Angiosarcoma; Apocrine Tubular Adenoma; Atypical Fibroxanthoma; Atypical Lipomatous Tumor and Liposarcoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cellular Neurothekeoma; Childhood Melanoma; Chondroid Lipoma; Collagenous Fibroma; Congenital Smooth Muscle Hamartoma; Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma; Cutaneous Mixed Tumor (Chondroid Syringoma); Cutaneous Myxoma and Angiomyxoma; Cutaneous Rhabdomyosarcoma; Cylindroma; Dermal Nerve Sheath Myxoma; Dermatofibrosarcoma Protuberans; Dermatomyofibroma; Desmoplastic Melanoma; Digital Fibromatosis (Infantile Digital Fibromatosis); Distinctive Dermal Clear Cell Mesenchymal Tumor; Eccrine Carcinoma; Eccrine Hamartomas; Ectopic Meningioma; Epithelioid Hemangioendothelioma; Epithelioid Histiocytoma; Epithelioid Sarcoma; Extramammary Paget Disease; Fibromatosis; Fibrosarcoma; Glomus Tumors; Granular Cell Tumor; Halo Nevi; Hibernoma; Histiocytic Sarcoma; Juvenile and Adult-type Xanthogranuloma; Keloid and Cellular Scar; Langerhans Cell Histiocytosis; Leiomyosarcoma; Leukemia Cutis; Lipoma; Low-Grade Fibromyxoid Sarcoma (Evans Tumor); Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Malignant Mixed Tumor; Melanoma In Situ, Superficial Spreading Type; Metastatic Skin Tumors; Mucosal Melanoma (Genital); Multicentric Reticulohistiocytosis; Myofibroma and Myofibromatosis; Myxofibrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Nasal Glial Heterotopia; Neurofibroma; Neuromas; Non-Langerhans Cell Histiocytoses; Oral Melanoma; Other Unusual and Rare Variants of Melanoma; Papillary Eccrine Adenoma; Paraganglioma-like Dermal Melanocytic Tumor; PEComas; Perineurioma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Plexiform Fibrohistiocytic Tumor; Polyvinylpyrrolidone Storage Disease; Primary Dermal Melanoma; Primary Neuroendocrine (Merkel Cell) Carcinoma; Pseudosarcomatous Fibroblastic Proliferations; Reticulohistiocytoma; Rosai-Dorfman Disease; Schwannoma (Neurilemmoma); Sebaceous Carcinoma; Sinonasal Melanoma; Spindle Cell and Pleomorphic Lipoma; Spindle Cell Hemangioma; Spiradenoma; Squamomelanocytic Tumor; Squamous Cell Carcinoma (and Variants); Superficial Acral Fibromyxoma; Superficial Malignant Peripheral Nerve Sheath Tumor; Toker Cell Hyperplasia


S100-A6


S100 calcium binding protein A6


calcyclin, S-100A6, CACY-100


Plexiform Fibrohistiocytic Tumor


S100-pla


S100 placental


S100P, S0084


Angiosarcoma


S100P


S100 placental


S100-pla, S0084


Angiomatoid Fibrous Histiocytoma; Angiosarcoma; Atypical Lipomatous Tumor and Liposarcoma; Congenital Smooth Muscle Hamartoma; Glomus Tumors


SCC


squamous cell carcinoma-related antigen


F2H7C


Basal Cell Carcinoma; Branchial Cleft Cyst; Metastatic Tumors to the Skin; Sebaceous Carcinoma; Squamous Cell Carcinoma (and Variants)


SNF5


member of SWI/SNF chromatin remodeling complex


BAF47/SNF5, INI1


Angiosarcoma


SOX9


SRY (sex-determining region Y)-box 9 protein


CMD1, CMPD1


Basal Cell Carcinoma


SOX10


SRY (sex-determining region Y)-box 10 protein



Childhood Melanoma; Desmoplastic Melanoma


Stem cell factor



SCF


Cutaneous and Systemic Mastocytosis


Surface immunoglobulins



Sig


Primary Cutaneous Follicle Center Lymphoma


Synaptophysin


major synaptic vesicle protein p38 antibody


SVP38, SY38, SNP-88, SYP, SYPH, Sypl, Syn p38


Dermal Nerve Sheath Myxoma; Ectopic Meningioma; Extramammary Paget Disease; Leukemia Cutis; Metastatic Skin Tumors; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sinonasal Melanoma; Squamous Cell Carcinoma In Situ (Bowen Disease)


TAG72


tumor-associated glycoprotein-72


CC49, B72.3, BRST-3


Metastatic Tumors to the Skin


TARC


thymus and activation regulated chemokine



Leukemia Cutis


TCL1


trophoblast membrane protein 1


NDOG1


Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia Cutis


TCR


T-cell receptor antigen


T_Cell_AG_R, Beta-F1, 8A3, BF1


Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Cutaneous Gamma-Delta T-cell Lymphoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Intravascular Large B-cell Lymphoma; Mycosis Fungoides (and Subtypes); Subcutaneous Panniculitis-like T-cell Lymphoma; Systemic T-cell and NK-cell Lymphomas Involving the Skin


TCR-β


Antibody directed toward the beta chain of the TCR-αβ heterodimer



Subcutaneous Panniculitis-like T-cell Lymphoma


TCR-βF1


specific for TCR beta chain constant region


Beta F1


Cutaneous Gamma-Delta T-cell Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma


TCR-δ-1


T-cell receptor delta chain 1



Cutaneous Gamma-Delta T-cell Lymphoma


TdT


terminal deoxynucleotidyl transferase


SEN28


Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia Cutis


Tenascin


Extracellular matrix glycoprotein


DB7, TN2


Cutaneous Mixed Tumor (Chondroid Syringoma)


Thyroglobulin


dimetric protein specific to thyroid gland


DAK-TG6


Metastatic Tumors to the Skin


TIA


T-cell intracellular antigen 1


NS/1-AG4, 2G9, TIA-1


Cutaneous Gamma-Delta T-cell Lymphoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Primary Cutaneous Anaplastic Large Cell Lymphoma; Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma; Subcutaneous Panniculitis-like T-cell Lymphoma


TIA-1


T-cell intracellular antigen 1


NS/1-AG4, 2G9, TIA


Adult T-cell Leukemia/Lymphoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Cutaneous Gamma-Delta T-cell Lymphoma; Extranodal NK/T-cell Lymphoma, Nasal Type; Leukemia Cutis; Lymphomatoid Papulosis; Subcutaneous Panniculitis-like T-cell Lymphoma


TRAP


tartrate-resistant acid phosphatase


26E5, 9C5


Giant Cell Tumor of Tendon Sheath; Neurofibroma; Nevoid Melanoma


Tryptase


serine proteinase contained in mast cells



Cutaneous and Systemic Mastocytosis


TTF-1


transcription termination factor


8G7G3/1, SPT-24, SC-13040


Lymphoepithelioma-like Carcinoma of the Skin (LELCS); Metastatic Skin Tumors; Metastatic Tumors to the Skin; Primary Neuroendocrine (Merkel Cell) Carcinoma; Sebaceous Carcinoma


TTF-1 cytoplasmic


transcription termination factorcytoplasmic


SC-13040_CP, 8G7G3/1_CP, TTF-1 CYTOP


Metastatic Skin Tumors


Tyrosinase


catalyzes production of melanin


NCL-TYROS, T311


Actinic Keratosis; Atypical Fibroxanthoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Childhood Melanoma; Desmoplastic Melanoma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Extramammary Paget Disease; Halo Nevi; Histiocytic Sarcoma; Melanoma In Situ, NOS; Oral Melanoma; PEComas; Sinonasal Melanoma; Superficial Malignant Peripheral Nerve Sheath Tumor; Other Unusual and Rare Variants of Melanoma


Uroplakin-3



AU 1, Uroplakin III


Extramammary Paget Disease


VEGF


vascular endothelial growth factor


JH121, 26503.11, VPF, VPF/VEGF, VEGFA, VEGF-C, RP 077, VEGFR-1, RP 076, VEGFR-2, 9D9, VEGFR-3, FLT-4


Infantile Hemangioma


VEGFR-3


vascular endothelial growth factor


JH121, 26503.11, VPF, VPF/VEGF, VEGFA, VEGF-C, RP 077, VEGFR-1, RP 076, VEGFR-2, 9D9, VEGF, FLT-4


Lymphangioma and Superficial Lymphangioma; Papillary Intralymphatic Angioendothelioma (Dabska Tumor); Retiform Hemangioendothelioma


Vimentin


major subunit protein of the intermediate filaments of mesenchymal cells


43BE8, 3B4, V10, V9, VIM-3B4, VIM


Atypical Fibroxanthoma; Cutaneous Mixed Tumor (Chondroid Syringoma); Dermatofibroma and Fibrous Histiocytoma; Distinctive Dermal Clear Cell Mesenchymal Tumor; Epithelioid Sarcoma; Fibrosarcoma; Fibrous Hamartoma of Infancy; Malignant Mixed Tumor; Multinucleate Cell Angiohistiocytoma; Myofibroma and Myofibromatosis; Neurofibroma; Oral Melanoma; Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor; Pleomorphic Fibroma; Sclerotic Fibroma; Sinonasal Melanoma; Squamous Cell Carcinoma (and Variants)


WT1


Wilms tumor gene-1


6F-H2, C-19


Metastatic Tumors to the Skin; Vascular Hamartomas; Verrucous Hemangioma

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Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Antibody Index
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