Pediatric COVID
Pediatric COVID Anna Martens Lael Yonker INTRODUCTION During the early phases of the coronavirus disease 2019 (COVID-19) pandemic, hospitals were inundated with adults infected with severe acute respiratory syndrome coronavirus…
Long COVID
Long COVID Roberto Patarca INTRODUCTION Beyond the human toll of its acute-phase and devastating socioeconomic impact, the still lingering severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2 pandemic1,2 that started toward the…
Genetic Determinants of Susceptibility and Resistance to SARS-CoV-2
Genetic Determinants of Susceptibility and Resistance to SARS-CoV-2 Maureen P. Martin Mary Carrington INTRODUCTION The clinical manifestations after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vary greatly across…
SARS-CoV-2 Variants
SARS-CoV-2 Variants Jacob E. Lemieux Jeremy Luban INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants are clusters of mutations that create distinct genetic lineages of SARS-CoV-2. Several such lineages…
Structure and Function of SARS-CoV-2 Spike Protein
Structure and Function of SARS-CoV-2 Spike Protein Bing Chen Jeremy Luban SARS-COV-2 AND CORONAVIRUS PHYLOGENY The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2…
Bat Coronaviruses
Bat Coronaviruses Chee Wah Tan Feng Zhu Akshamal Gamage Lin-Fa Wang INTRODUCTION Bats are the only flying mammals with more than 1,400 known species and are regarded as the second…
Molecular Biology of SARS-CoV-2
Molecular Biology of SARS-CoV-2 Roberto Patarca William A. Haseltine INTRODUCTION Coronaviruses are the largest group within the Nidovirales order that includes eleven families1 and pathogens of veterinary and medical importance….
Epidemiology of COVID-19
Epidemiology of COVID-19 Sten H. Vermund Mahima Kaur INTRODUCTION At the end of 2019, China reported a global outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome…
