Precursors Classification ▪ The classifications used for precursors of cervical invasive squamous cell carcinoma (ISqCC), in order of their historical development, are: (1) dysplasia/carcinoma in situ (CIS); (2) cervical intraepithelial…
Tumor-Like Lesions Metaplasias and Ectopias Squamous Metaplasia ( Figs. 4.1 – 4.2 ) ■ This normal process within the transitional zone of postpubertal women results in the replacement of endocervical…
Tumor-Like and Inflammatory Lesions Condyloma Acuminatum ▪ These resemble their vulvar counterparts ( Chapter 1 ) except for a more frequent occurrence of flat condylomas and those with a ‘spiked’…
Viral Infections Human Papillomavirus (Hpv) (Including Condyloma Acuminatum) Clinical and gross features ( Fig. 1.1 ) ▪ Sexually transmitted HPV (usually low-risk types, especially HPV 6 and 11) is the…
Squamous Cell Carcinoma and Its Precursors Vulvar Intraepithelial Neoplasia (VIN) Terminology ■ The main types of VIN – usual VIN (uVIN) and differentiated VIN (dVIN) – each have distinctive clinical…
