Capsaicin as New Orally Applicable Gastroprotective and Therapeutic Drug Alone or in Combination with Nonsteroidal Anti-Inflammatory Drugs in Healthy Human Subjects and in Patients
Fig. 9.1 Inhibition of gastric acid basal output (BAO) by capsaicin in 16 healthy human subjects. (After Mózsik et al. 2005) 9.3.2 Affinity and Intrinsic Affinity Curves for the Capsaicin, Muscarinic…
Capsaicin Receptor as Target of Calcitonin Gene-Related Peptide in the Gut
Fig. 10.1 Schematic view of the CGRP receptor that consists of calcitonin receptor-like peptide (CLR), receptor activity modifying protein 1 (RAMP1), and receptor component protein (RCP) The human C-terminal fragment of…
The Potential Antitumor Effects of Capsaicin
Fig. 8.1 Structure of capsaicin. Capsaicin has three main moieties: vannillyl (methylcatechol group), amide bond, and an alkyl side chain Capsaicin is absorbed very rapidly by a nonactive process from the…
Capsaicin and Sensory Neurones: A Historical Perspective
Fig. 1.1 Chemical structure of some exogenous and endogenous agonists of the transient receptor potential vanilloid type-1 (TRPV1) capsaicin receptor The first paper on studying the pharmacological effects of capsaicin was…
Capsaicin for Osteoarthritis Pain
Study, duration n Age (years) Sex (M:F) OA site Formulation Outcomes Rate of application site burning Deal 1991 (Deal et al. 1991) 4 weeks 70 61 25M:45F Knee 0.025 % capsaicin VAS…