Squamous Cell Carcinoma Key Facts Terminology Malignant epithelial neoplasm with squamous (epidermoid) differentiation Macroscopic Features Central or peripheral tumors White or light brown in color with homogeneous cut surface; cut…
Adenocarcinoma Key Facts Terminology Malignant epithelial neoplasm with glandular differentiation Etiology/Pathogenesis Close association with tobacco smoking Clinical Issues Cough Weight loss Chest pain Difficulty breathing Macroscopic Features Peripheral or central…
Mucinous (“Colloid”) Carcinoma Key Facts Terminology Mucinous cystadenoma, mucinous cystic tumor, multilocular cystic carcinoma, mucinous cystic tumor of borderline malignancy Macroscopic Features Well-defined tumor mass with mucoid consistency, solid &/or…
Endometrioid-like Carcinoma Key Facts Terminology Malignant epithelial neoplasms with features mimicking secretory endometrium Clinical Issues Symptoms Cough Dyspnea Hemoptysis Chest pain Prognosis Depends on clinical and pathological stage Treatment options…
Signet Ring Cell Carcinoma Key Facts Terminology Synonym: Adenocarcinoma with signet ring cells Definition Non-small cell carcinoma with signet ring cells similar to those described in gastrointestinal tract Clinical Issues…
Bronchioloalveolar Cell Carcinoma Key Facts Terminology Bronchioloalveolar cell carcinoma (BAC) Adenocarcinoma with BAC pattern and no evidence of stromal, vascular, or pleural invasion Essentially, current definition is that of in…
Clear Cell “Sugar” Tumor (PEComa) Key Facts Terminology Benign intrapulmonary neoplasm with prominent clear cells Etiology/Pathogenesis Myo-melanocytic differentiation (PEComa) Clinical Issues Although tumor is more common in adults, it has…
Sclerosing Hemangioma (Pneumocytoma) Key Facts Terminology Pneumocytoma Etiology/Pathogenesis Tumor appears to have pneumocytic differentiation, yet histogenesis remains unclear Clinical Issues Incidence More common among women Tumor is more common in…
Granular Cell Tumor Key Facts Terminology Granular cell tumor (GCT) Benign neoplasm composed of medium-sized cells with prominent granular cytoplasm Malignant counterpart shows similar histology but with nuclear atypia and…
Overview of Malignant Epithelial Neoplasms of the Lung Poorly differentiated non-small cell carcinoma of the lung shows sheets of large, atypical cells with large nuclei and prominent nucleoli and without…
