Basicmedical Key

Fungus Pulmonary fungal infections may be endemic or opportunistic. The truly pathogenic (endemic) fungi may infect healthy as well as immunocompromised hosts, whereas the opportunistic fungi usually infect immunocompromised hosts…

Lung Pathology in Transplantation of Other Organs Anna Sienko Due to immunosuppressive therapy, the lung is a frequent site of opportunistic infection in organ transplants of all types and is…

Parasites Several parasites may be found in the lungs and associated tissues of humans. Of these, only two infect human lungs by preference: Dirofilaria immitis and Paragonimus sp. The remainder…

Other Lung Transplant-Related Pathology Anna Sienko Drug reactions, variable tissue reactions to rejection, and a host of other findings may be observed in the lungs of lung transplant recipients. Alveolar…

Organizing Pneumonia in the Transplanted Lung Anna Sienko Organizing pneumonia, or bronchiolitis obliterans organizing pneumonia, may result from any of multiple potential causes in lung transplant patients, including causes that…

Transplant-Related Infections Anna Sienko Lung transplant patients are susceptible to opportunistic infections, and more than 50% experience one or more episodes of infection resulting in increased morbidity and occasional fatality….

Primary Graft Failure Anna Sienko Primary graft failure of a transplanted lung may be due to donor, recipient, or surgical factors. Ischemia-reperfusion injury with activation of recipient innate immunity usually…

Chronic Lung Transplant Rejection Anna Sienko Late airway rejection (chronic rejection) is usually seen in late post-transplant patients (months to years) and is the most common cause of morbidity and…

Complications Involving the Anastomosis Anna Sienko Bronchial and vascular anastomotic complications usually occur within a week of lung transplantation, with patients demonstrating increased dyspnea, pulmonary arterial hypertension, and hypoxia. Ischemic…

Antibody-Mediated (Hyperacute and Humoral) Rejection of the Transplanted Lung Anna Sienko Roberto Barrios Hyperacute rejection and humoral rejection are antibody-mediated forms of rejection that are recognized in other solid organ…