Fig. 10.1
Top panel reveals an unremarkable epidermis and papillary dermis. The reticular dermis contains a dense collection of cells. Bottom panel reveals a monomorphous infiltrate of small lymphocytes. The biopsy was obtained from a lesion of lymphocytoma cutis on the face
Nomenclature
Cutaneous lymphoid hyperplasia, reactive lymphoid hyperplasia, lymphocytoma cutis , Spiegler-Fendt sarcoid, pseudolymphoma of Spiegler-Fendt, and lymphadenosis benigna cutis are all terms that describe lesions in which there is a dense proliferation of lymphocytes reminiscent of lymphoma but the infiltrate is not malignant. Recently, the term “pseudolymphoma” became widely used for lesions that would have been referred to in the past as one of the other terms.
If There Are No Differences Between the Various Terms,Should We Use One Term Only?
The answer is no. The term lymphocytoma cutis, for example, is best used clinically to describe patients who present with one or less commonly few, red, smooth-fixed nodules on their face. The usefulness of the term pseudolymphoma may be debated.
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