V
vaccination injection of attenuated (i.e. live) or killed (i.e. dead) culture of a specific microorganism/its exotoxin to induce host immunity to the causative agent
vaccine preparation designed to act as disease prophylaxis
vacuole clear space within cell cytoplasm, containing foreign material
valency combining power of an atom, determined by number of electrons in its outer shell
valgus positional variant characterized by turning outwards of a part
valgus pad filler pad; D filler (see Table P1); clinical/orthotic pad; plantar part of pad infills/cushions plantar medial longitudinal arch; medial flange extends along medial aspect of arch; functions within shoe (in conjunction with medial heel wedge) creating degree of dynamic inversion of foot during gait
valgus rearfoot see everted rearfoot
Valleix sign see sign, Valleix’
Valsalva’s test see test, Valsalva’s
valve fold/or flap in lining of a tubular structure; prevents content reflux
vamp part of shoe upper; see Table F6
variant Creutzfeldt–Jakob disease; variant CJD see disease, Creutzfeldt–Jakob
varicella chickenpox, causing marked vesicular eruptions of all skin areas, including feet
varus heel varus rearfoot, see rearfoot varus
vasa nervosum; vasa nervorum system of nutrient blood vessels supplying nerve fibres
vasa vasorum system of nutrient blood vessels supplying blood and lymphatic vessel walls
vascular corn see heloma vasculare; Table C14
vascular disease see disease, peripheral vascular Tables F1 and F3
vascular endothelium see tunica intima
vascularization; neovascularization new blood vessel formation
vasculitis angiitis; blood vessel inflammation
vasoactive influencing blood vessel tone/caliber
vasoconstrictor agent inducing blood vessel narrowing (see adrenaline; nitric oxide); nicotine in cigarette smoke is a powerful vasoconstrictor and exacerbates all forms of vascular disease
vasodilator agent causing dilatation of blood vessels
vasomotor agent/nerve impulse causing blood vessel constriction/dilation
vasopressor agent/nerve causing vasoconstriction/increase in blood pressure
vasospasm; angiospasm tunica media contraction
vasospastic disorders pathological conditions characterized by spasmodic vasoconstriction, e.g. Raynaud’s disease (see Table R4)
vasovagal attack faint, i.e. transient unconsciousness due to sudden drop in blood pressure, in response to fear/fright (see syncope)
vastus intermedius muscle at anterior area of femur, partly fused with vasti medialis and lateralis
vastus lateralis muscle at lateral side of femur; partly fused with vastus intermedius
vastus medialis muscle at medial side of femur; partly fused with vastus intermedius
vegetative reproduction reproduction by budding, not involving sexual cells
vehicle non-active part of a medicament, i.e. carrier of active ingredient; may act as an agent in its own right, e.g. 3% salicylic acid in 70% industrial methylated spirit (IMS) is used to treat tinea pedis with hyperhidrosis; both active ingredient (3% salicylic acid) and vehicle (70% IMS) have astringent/antifungal properties (Tables V1 and V2)
Vehicle type | Comment |
---|---|
Applications | Viscous solutions, emulsions or suspensions for application to the skin or nails |
Collodions | Clear paints carrying an active ingredient applied to the skin and left to dry to a flexible film (e.g. ichthammol in collodion) |
Creams | Emulsions of oil and water generally well absorbed into the skin surface; creams are less greasy and easier to apply than ointments |
Gels | Active ingredients within a suitable hydrophilic or hydrophobic base; they have a high water content |
Lotions | A cooling preparation for external application, to the skin, formed as a liquid suspension often in an industrial methylated spirit or alcohol base A shake lotion contains an insoluble powder in a liquid that must be shaken before use to disperse the powder evenly throughout the liquid medium, e.g. calamine lotion |
Ointments | Greasy preparations that are usually insoluble in water; a salve or unguent; a semisolid preparation containing a medicinal agent in a fatty or waxy base, intended for topical application; the greasy base of an ointment (usually formulated from soft paraffin, or a combination of soft and hard paraffin) acts as an occlusive medium and makes it especially suitable for use on dry or anhydrous skin Water-soluble ointments are based on macrogols and can be washed off |
Pastes | Stiff preparations containing a high proportion of fine solids, such as zinc oxide and starch; they are less occlusive than ointments and can be used to protect lichenified, inflamed or excoriated skin (e.g. in eczema) |
Dusting powders | Fine powders, e.g. talc, applied to apposing skin surfaces; they should not be used on moist or weeping surfaces |
Base agents | ||
---|---|---|
Starch, Chalk, Magnesium carbonate, Kaolin, Talc, Zinc oxide, Zinc stearate The base agent should augment the action of the active ingredient | ||
Active ingredients | ||
Examples | Action | Indicated use |
Boric acid 5% Salicylic acid 3–10% Alum 10% Benzocaine 10% Calamine Chlorphensin 1% Menthol 2% Phenol 2.5% Sodium perborate 15% Sodium poly-metaphosphate 5% Benzoin 10% Undecenoic acid 2% Zinc undecenoate 10% | Active against foetid bacteria Astringent, antiseptic, antifungal Strongly astringent and deodorant Analgesic and antipruritic Soothing, absorbent Fungicidal Fungicidal Antipruritic and fungicidal Antiseptic Astringent Astringent Fungicidal Fungicidal | Bromidrosis Hyperhidrosis and mild fungal skin infection Hyperhidrosis and bromidrosis Irritant skin conditions Irritant skin conditions Fungal infections Fungal infections Irritant fungal infections Mild skin infection Prophylaxis of fungal infection Hyperhidrosis Fungal infection Fungal infection |
Velcro fastenings Velcro-covered straps used in place of laces; allows the shoe to accommodate to a foot whose dimensions alter throughout the day, e.g. oedema accumulation (see Table F10)
vena cava vein trunks carrying deoxygenated blood from the body to the right atrium