Undifferentiated Carcinoma



Undifferentiated Carcinoma


Mari Mino-Kenudson, MD









This gross photograph of an undifferentiated carcinoma with osteoclast-like giant cells has a soft, fleshy cut surface with prominent hemorrhage image and necrosis image.






This undifferentiated carcinoma has a prominent sarcomatoid component featuring plump spindle cells in a fascicular pattern.


TERMINOLOGY


Synonyms



  • Pleomorphic carcinoma, pleomorphic large cell carcinoma, pleomorphic giant cell carcinoma


  • Undifferentiated carcinoma with osteoclast-like giant cells



    • Giant cell tumor of pancreas


    • Osteoclast-like giant cell tumor of pancreas


Definitions



  • Malignant epithelial neoplasm with significant component showing no definite differentiation



    • Wide range of morphologic findings ranging from pleomorphic epithelioid cells to multinucleated giant cells to spindle cells


    • Multiple patterns often present within same tumor

Jul 7, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Undifferentiated Carcinoma
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