Tree (Oil): Melaleuca alternifolia (Maiden & Betche) Cheel


Tea Tree (Oil)


Melaleuca alternifolia (Maiden & Betche) Cheel


Synonym:


M. linariifolia var. alternifolia Maiden & Betche


Other common names:


Australian tea tree; ti tree


Family:


Myrtaceae


Drug name(s):


Melaleucae alternifoliae aetherolium


Botanical drug used:


Essential oil, extracted by steam distillation of the leaves and terminal branches (twigs)


Main chemical compounds:


There is variability in the chemical profile of tea tree oil and six chemotypes (varieties) of M. alternifolia are recognised, each with a distinct chemical composition. The most highly valued varieties contain at least 40% terpinen-4-ol. There is an international standard that stipulates ranges for 14 constituents of the oil, including terpinen-4-ol, terpinene, terpinoline, cineole, terpineol, cymene, pinene and limonene. The composition of the oil may alter considerably during storage, as its stability is affected by light, heat, air and moisture (Carson et al. 2006; Tisserand and Young 2014).


Clinical evidence:


Clinical studies assessing the efficacy of tea tree oil in the treatment of acne have demonstrated that 5% tea tree oil reduces the number of inflamed lesions on a par with benzoyl peroxide, but with significantly fewer side effects (Carson et al. 2006).


Pre-clinical evidence and mechanisms of action:

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Nov 25, 2016 | Posted by in PHARMACY | Comments Off on Tree (Oil): Melaleuca alternifolia (Maiden & Betche) Cheel

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